Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | LPO | P22079 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | DTYMK | P23919 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8950560 | 0.89 | MEN1 (0.43) | MEN1KMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL2430037 | 0.83 | KMT2A (0.35) | MEN1KMT2AALDH1A1LMNACYP1A2 | |
| SCHEMBL13527339 | 0.82 | MEN1 (0.40) | MEN1KMT2AL3MBTL1MAPK1HPGD | |
| SCHEMBL3761042 | 0.79 | LMNA (0.40) | MEN1KMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL1152756 | 0.78 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1CYP1A2MAPK1 | |
| SCHEMBL14335874 | 0.76 | KMT2A (0.40) | MEN1KMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL14405323 | 0.74 | ALDH1A1 (0.34) | MEN1KMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL14405314 | 0.74 | SMN1; SMN2 (0.40) | MEN1KMT2AALDH1A1LMNACYP1A2 | |
| SCHEMBL3169404 | 0.74 | MEN1 (0.36) | MEN1KMT2AALDH1A1LMNACYP1A2 | |
| SCHEMBL7778467 | 0.73 | TSHR (0.47) | ALDH1A1LMNAL3MBTL1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629084-B2 | Iodine-phenyl-substituted cyclic cetoenols | BAYER CROPSCIENCE AG (DE) | 2014-01-14 | — | — | US | disclosed |
| US-8629084-B2 | Iodine-phenyl-substituted cyclic cetoenols | BAYER CROPSCIENCE AG (DE) | 2014-01-14 | — | — | US | disclosed |
| US-8629084-B2 | Iodine-phenyl-substituted cyclic cetoenols | BAYER CROPSCIENCE AG (DE) | 2014-01-14 | — | — | US | disclosed |
| US-20100009850-A1 | Iodine-phenyl-substituted cyclic cetoenols | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2010-01-14 | — | — | US | disclosed |
| US-20100009850-A1 | Iodine-phenyl-substituted cyclic cetoenols | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2010-01-14 | — | — | US | disclosed |
| US-20100009850-A1 | Iodine-phenyl-substituted cyclic cetoenols | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009850-A1 | Iodine-phenyl-substituted cyclic cetoenols | KCNE1, KCNH3, KCNH2 | MEN1 3861/4885KMT2A 1203/4885ALDH1A1 3372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.