Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8950560 | 0.85 | MEN1 (0.43) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3169396 | 0.83 | MEN1 (0.35) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL10309326 | 0.79 | KMT2A (0.33) | KMT2AMEN1OPRM1OPRK1ALDH1A1 | |
| SCHEMBL13527339 | 0.79 | MEN1 (0.40) | KMT2AMEN1SMN1; SMN2HPGDNPSR1 | |
| SCHEMBL3761042 | 0.76 | LMNA (0.40) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL1152756 | 0.75 | ALDH1A1 (0.38) | KMT2AMEN1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL14335874 | 0.73 | KMT2A (0.40) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL2431064 | 0.73 | MAPT (0.35) | KMT2AMEN1PKMALDH1A1KDM4E | |
| SCHEMBL4575872 | 0.72 | KDM4E (0.35) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL14405323 | 0.72 | ALDH1A1 (0.34) | KMT2AMEN1ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8541617-B2 | Cycloalkylphenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2013-09-24 | — | — | US | disclosed |
| US-8541617-B2 | Cycloalkylphenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2013-09-24 | — | — | US | disclosed |
| US-8541617-B2 | Cycloalkylphenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2013-09-24 | — | — | US | disclosed |
| US-20120178927-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2012-07-12 | — | — | US | disclosed |
| US-20120178927-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2012-07-12 | — | — | US | disclosed |
| US-20120178927-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2012-07-12 | — | — | US | disclosed |
| US-8013172-B2 | Cycloalkylphenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-09-06 | — | — | US | disclosed |
| US-8013172-B2 | Cycloalkylphenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-09-06 | — | — | US | disclosed |
| US-8013172-B2 | Cycloalkylphenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-09-06 | — | — | US | disclosed |
| EP-2186791-A1 | Cycloalkyl-phenyl-substituted cyclic ketoenoles | Bayer CropScience AG (DE) | 2010-05-19 | — | — | EP | disclosed |
| EP-2186805-A1 | Cycloalkyl-phenyl-substituted cyclic ketoenoles | Bayer CropScience AG (DE) | 2010-05-19 | — | — | EP | disclosed |
| EP-2186805-A1 | Cycloalkyl-phenyl-substituted cyclic ketoenoles | Bayer CropScience AG (DE) | 2010-05-19 | — | — | EP | disclosed |
| EP-2186791-A1 | Cycloalkyl-phenyl-substituted cyclic ketoenoles | Bayer CropScience AG (DE) | 2010-05-19 | — | — | EP | disclosed |
| EP-2184275-A1 | Cycloalkyl-phenyl-substituted cyclic ketoenoles | Bayer CropScience AG (DE) | 2010-05-12 | — | — | EP | disclosed |
| EP-2184275-A1 | Cycloalkyl-phenyl-substituted cyclic ketoenoles | Bayer CropScience AG (DE) | 2010-05-12 | — | — | EP | disclosed |
| US-20090305891-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2009-12-10 | — | — | US | disclosed |
| US-20090305891-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2009-12-10 | — | — | US | disclosed |
| US-20090305891-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2009-12-10 | — | — | US | disclosed |
| WO-2007096058-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2007-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178927-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | PHYKPL, KCNE1, PIKFYVE | KMT2A 936/4885MEN1 4700/4885PDE4B 1885/4885 |
| US-20090305891-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | PHYKPL, KCNE1, PKM | KMT2A 1396/4885MEN1 4818/4885PDE4B 1923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.