Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL736680 | 0.82 | HSD17B10 (0.61) | HSD17B10HPGDCYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL8229173 | 0.82 | SMN1; SMN2 (0.37) | HSD17B10CYP3A4ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL12529998 | 0.82 | SMN1; SMN2 (0.37) | HSD17B10CYP3A4ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL29290531 | 0.80 | ADRB1 (0.50) | HSD17B10HPGDCYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL11290173 | 0.78 | ALDH1A1 (0.45) | HSD17B10HPGDCYP3A4CRHBPCRHR2 | |
| SCHEMBL28238550 | 0.77 | CYP3A4 (0.50) | HPGDCYP3A4ALDH1A1CYP1A2ALOX15 | |
| SCHEMBL12529817 | 0.77 | LMNA (0.35) | HSD17B10CYP3A4CYP1A2CYP2C9ALOX15 | |
| SCHEMBL9334010 | 0.76 | UGT2B7 (0.46) | HSD17B10ALDH1A1ALOX15HIF1ATSHR | |
| SCHEMBL9331671 | 0.76 | UGT2B7 (0.46) | HSD17B10ALDH1A1ALOX15HIF1ATSHR | |
| SCHEMBL9331613 | 0.76 | UGT2B7 (0.46) | HSD17B10ALDH1A1ALOX15HIF1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502073-A | INSECTICIDES OR ANTHELMINTICS | THE WELLCOME FOUNDATION (GB) | 1996-03-26 | — | — | US | disclosed |
| EP-0294229-B1 | NOVEL HETEROCYCLIC PESTICIDAL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-12-02 | — | — | EP | disclosed |
| EP-0294229-A2 | Novel heterocyclic pesticidal compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1988-12-07 | — | — | EP | disclosed |