Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15934965 | 0.85 | LMNA (0.38) | ALDH1A1HSD17B10CYP3A4EIF4A3CYP1A2 | |
| SCHEMBL23695445 | 0.83 | EIF4A3 (0.36) | ALDH1A1HSD17B10CYP3A4EIF4A3CYP1A2 | |
| SCHEMBL12889907 | 0.82 | EIF4A3 (0.40) | ALDH1A1HSD17B10EIF4A3CYP1A2CYP2C9 | |
| SCHEMBL10346107 | 0.80 | EIF4A3 (0.39) | HSD17B10EIF4A3CYP1A2CYP2C9ALOX15 | |
| SCHEMBL21281618 | 0.80 | EIF4A3 (0.39) | HSD17B10EIF4A3CYP1A2CYP2C9ALOX15 | |
| SCHEMBL15713188 | 0.80 | EIF4A3 (0.39) | HSD17B10EIF4A3CYP1A2CYP2C9ALOX15 | |
| SCHEMBL15713194 | 0.79 | HDAC4 (0.39) | ALDH1A1HPGDEIF4A3SMN1; SMN2 | |
| SCHEMBL8950753 | 0.78 | HSD17B10 (0.43) | ALDH1A1HSD17B10CYP3A4HPGDCRHBP | |
| SCHEMBL17553336 | 0.78 | ALDH1A1 (0.41) | ALDH1A1HSD17B10CYP3A4HPGDCRHBP | |
| SCHEMBL25443271 | 0.78 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CYP3A4HPGDEIF4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230337677-A1 | ARYL AND PYRIDYL AMIDE PESTICIDES AND COMPOSITIONS THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2023-10-26 | — | — | US | disclosed |
| US-20230337677-A1 | ARYL AND PYRIDYL AMIDE PESTICIDES AND COMPOSITIONS THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2023-10-26 | — | — | US | disclosed |
| US-20230151060-A1 | CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-05-18 | — | — | US | disclosed |
| US-20230151060-A1 | CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-05-18 | — | — | US | disclosed |
| US-11225469-B2 | Inhibitors of phosphoglycerate dehydrogenase (PHGDH) and uses thereof | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2022-01-18 | — | — | US | disclosed |
| EP-3534709-B1 | SUBSTITUTED SULFONYLAMIDE FOR COMBATING ANIMAL PESTS | BAYER AG (DE) | 2021-06-16 | — | — | EP | disclosed |
| US-10820591-B2 | Substituted sulfonyl amides for controlling animal pests | BAYER AKTIENGESELLSCHAFT (DE) | 2020-11-03 | — | — | US | disclosed |
| US-20190269134-A1 | SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS | BAYER AKTIENGESELLSCHAFT (DE) | 2019-09-05 | — | — | US | disclosed |
| US-20180105508-A1 | INHIBITORS OF PHOSPHOGLYCERATE DEHYDROGENASE (PHGDH) AND USES THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2018-04-19 | — | — | US | disclosed |
| US-20180105508-A1 | INHIBITORS OF PHOSPHOGLYCERATE DEHYDROGENASE (PHGDH) AND USES THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2018-04-19 | — | — | US | disclosed |
| EP-2916840-B1 | SUBSTITUTED GEMCITABINE ARYL AMIDE ANALOGS | NUCORION PHARMACEUTICALS INC (US) | 2017-11-01 | — | — | EP | disclosed |
| US-9744186-B2 | Substituted gemcitabine aryl amide analogs | NUCORION PHARMACEUTICALS, INC. (US) | 2017-08-29 | — | — | US | disclosed |
| EP-3087155-A1 | CONTROL OF SUSTAINED CASING PRESSURE IN WELLBORE ANNULI | Albemarle Corporation (US) | 2016-11-02 | — | — | EP | disclosed |
| US-20160289527-A1 | CONTROL OF SUSTAINED CASING PRESSURE IN WELLBORE ANNULI | ALBEMARLE CORP (US) | 2016-10-06 | — | — | US | disclosed |
| WO-2015100004-A1 | CONTROL OF SUSTAINED CASING PRESSURE IN WELLBORE ANNULI | ALBEMARLE CORPORATION (US) | 2015-07-02 | — | — | WO | disclosed |
| US-8889710-B2 | Parasiticidal dihydroisoxazole compounds | ELI LILLY AND COMPANY (US) | 2014-11-18 | — | — | US | disclosed |
| WO-2014074725-A1 | SUBSTITUTED GEMCITABINE ARYL AMIDE ANALOGS | OHIO STATE INNOVATION FOUNDATION (US) | 2014-05-15 | — | — | WO | disclosed |
| US-20140107149-A1 | PARASITICIDAL DIHYDROISOXAZOLE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2014-04-17 | — | — | US | disclosed |
| US-20070049603-A1 | Raf inhibitor compounds and methods of use thereof | ARRAY BIOPHARMA INC. | 2007-03-01 | — | — | US | disclosed |
| EP-0061720-A1 | Process for the selective aliphatic chlorination of alkylbenzenes | THE DOW CHEMICAL COMPANY (US) | 1982-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151060-A1 | CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION | KRAS, NRAS, HRAS | ALDH1A1 4838/4885HSD17B10 4794/4885CYP3A4 4653/4885 |
| US-20070049603-A1 | Raf inhibitor compounds and methods of use thereof | BRAF, RAF1, ARAF | ALDH1A1 1842/4885HSD17B10 2499/4885CYP3A4 3785/4885 |
| US-11225469-B2 | Inhibitors of phosphoglycerate dehydrogenase (PHGDH) and uses thereof | PHGDH, PGD, PGK1 | ALDH1A1 819/4885HSD17B10 200/4885CYP3A4 1161/4885 |
| US-20140107149-A1 | PARASITICIDAL DIHYDROISOXAZOLE COMPOUNDS | DHODH, DDT, CYP51A1 | ALDH1A1 714/4885HSD17B10 808/4885CYP3A4 358/4885 |
| US-20180105508-A1 | INHIBITORS OF PHOSPHOGLYCERATE DEHYDROGENASE (PHGDH) AND USES THEREOF | PHGDH, PGD, PGK1 | ALDH1A1 778/4885HSD17B10 238/4885CYP3A4 1314/4885 |
| US-20190269134-A1 | SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS | MLYCD, STOM, DDT | ALDH1A1 2367/4885HSD17B10 3195/4885CYP3A4 2644/4885 |
| US-20230337677-A1 | ARYL AND PYRIDYL AMIDE PESTICIDES AND COMPOSITIONS THEREOF | DDT, ACHE, AHR | ALDH1A1 2254/4885HSD17B10 2974/4885CYP3A4 151/4885 |
| US-10820591-B2 | Substituted sulfonyl amides for controlling animal pests | MLYCD, STOM, DDT | ALDH1A1 2367/4885HSD17B10 3195/4885CYP3A4 2644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.