Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10650894 | 0.74 | ALDH1A1 (0.43) | TSHRALDH1A1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL6051764 | 0.73 | ALDH1A1 (0.41) | TSHRALDH1A1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL2390211 | 0.73 | TSHR (0.38) | TSHRALDH1A1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL30179645 | 0.73 | TSHR (0.39) | TSHRALDH1A1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL3645580 | 0.73 | TSHR (0.38) | TSHRALDH1A1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL5400750 | 0.73 | TSHR (0.38) | TSHRALDH1A1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL4744554 | 0.73 | TSHR (0.38) | TSHRALDH1A1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL8950934 | 0.73 | TSHR (0.38) | TSHRALDH1A1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL1825593 | 0.72 | TSHR (0.46) | TSHRALDH1A1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL10193791 | 0.71 | ALDH1A1 (0.40) | TSHRALDH1A1MAPK1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295639-B1 | Fluorine-containing alicyclic and aromatic cyclic compounds, process thereof and adhesive composition containing the compounds | DAIKIN IND LTD (JP) | 1993-12-01 | — | — | EP | disclosed |