⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20658212 | 0.92 | TSHR (0.33) | — | |
| SCHEMBL20658199 | 0.82 | TSHR (0.42) | — | |
| SCHEMBL14914835 | 0.80 | RAB9A (0.33) | — | |
| SCHEMBL2430231 | 0.72 | TSHR (0.43) | — | |
| SCHEMBL1042228 | 0.72 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL135552 | 0.71 | TSHR (0.46) | — | |
| SCHEMBL28438742 | 0.71 | TSHR (0.46) | — | |
| SCHEMBL2139803 | 0.68 | TSHR (0.43) | — | |
| SCHEMBL3577655 | 0.68 | TSHR (0.43) | — | |
| Hydrochloric Acid SCHEMBL336735 | 0.68 | TSHR (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745071-A1 | 4-AMINO 6-SUBSTITUTED MYCOPHENOLIC ACID AND DERIVATIVES WITH IMMUNOSUPPRESSIVE ACTIVITY | SYNTEX (U.S.A.) INC. (US) | 1996-12-04 | — | — | EP | disclosed |
| EP-0745075-A1 | 6-SUBSTITUTED MYCOPHENOLIC AND DERIVATIVES WITH IMMUNOSUPPRESSIVE ACTIVITY | SYNTEX (U.S.A.) INC. (US) | 1996-12-04 | — | — | EP | disclosed |
| US-5554612-A | IMMUNOSUPPRESSANTS, VIRICIDES, ANTITUMOR AND ANTIINFLAMMATORY AGENTS | SYNTEX INC (US) | 1996-09-10 | — | — | US | disclosed |
| US-5536747-A | ENZYME INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1996-07-16 | — | — | US | disclosed |
| US-5525602-A | TREATING INFLAMMATORY DISEASES, PREVENTING ALLOGRAFT REJECTION, AUTOIMMUNE DISEASES | SYNTEX (U.S.A.) INC. (US) | 1996-06-11 | — | — | US | disclosed |
| WO-1995022534-A1 | 4-AMINO 6-SUBSTITUTED MYCOPHENOLIC ACID AND DERIVATIVES WITH IMMUNOSUPPRESSIVE ACTIVITY | SYNTEX (U.S.A.) INC. (US) | 1995-08-24 | — | — | WO | disclosed |
| WO-1995022536-A1 | 6-SUBSTITUTED MYCOPHENOLIC AND DERIVATIVES WITH IMMUNOSUPPRESSIVE ACTIVITY | SYNTEX (U.S.A.) INC. (US) | 1995-08-24 | — | — | WO | disclosed |
| US-5444072-A | Useful in treatment of autoimmune disorders, psoriasis, inflammatory diseases, rheumatoid arthritis | SYNTEX (U.S.A.) INC. (US) | 1995-08-22 | — | — | US | disclosed |