Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20658212 | 0.78 | TSHR (0.33) | TSHRALDH1A1LMNA | |
| SCHEMBL7109247 | 0.77 | TSHR (0.55) | TSHRALDH1A1 | |
| Water SCHEMBL3700992 | 0.76 | TSHR (0.43) | TSHRALDH1A1LMNA | |
| SCHEMBL1042228 | 0.74 | SMN1; SMN2 (0.31) | TSHRLMNA | |
| SCHEMBL28438742 | 0.73 | TSHR (0.46) | TSHRALDH1A1LMNA | |
| SCHEMBL135552 | 0.73 | TSHR (0.46) | TSHRALDH1A1LMNA | |
| SCHEMBL8951503 | 0.72 | — | — | |
| SCHEMBL14914835 | 0.72 | RAB9A (0.33) | LMNA | |
| Hydrochloric Acid SCHEMBL336735 | 0.70 | TSHR (0.43) | TSHRALDH1A1LMNA | |
| SCHEMBL3577655 | 0.70 | TSHR (0.43) | TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4655293-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | Syngenta Crop Protection AG (CH) | 2025-12-03 | — | — | EP | disclosed |
| WO-2024156664-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2024-08-02 | — | — | WO | disclosed |
| CN-117836301-A | 2, 2-difluoro-5H- [1,3] dioxolo [4,5-F ] isoindol-7-one derivatives as pesticides | 先正达农作物保护股份公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-116075226-A | Pesticidally active heterocyclic derivatives with sulfur containing substituents | 先正达农作物保护股份公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-116056577-A | Pesticidally active heterocyclic derivatives with sulfur containing substituents | 先正达农作物保护股份公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-110526832-B | Method for preparing polysubstituted alicyclic compound | 浙江师范大学 | 2022-06-10 | — | — | CN | disclosed |
| CN-106715428-B | Pesticidally active tetracyclic derivatives with sulfur-containing substituents | 先正达参股股份有限公司 | 2020-07-07 | — | — | CN | disclosed |
| US-20200207741-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | HOFFMANN-LA ROCHE INC. | 2020-07-02 | — | — | US | disclosed |
| US-10640491-B2 | Inhibitors of bruton's tyrosine kinase | HOFFMANN-LA ROCHE INC. (US) | 2020-05-05 | — | — | US | disclosed |
| US-20200055850-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-02-20 | — | — | US | disclosed |
| US-20050288270-A1 | New aminopyridine derivatives and their use as pharmaceuticals | PFIZER INC | 2005-12-29 | — | — | US | disclosed |
| WO-2005115985-A1 | AMINOPYRIDINE DERIVATIVES AS SELECTIVE DOPAMINE D3 AGONISTS | PFIZER LIMITED (GB) | 2005-12-08 | — | — | WO | disclosed |
| US-20050182144-A1 | Novel vitamin D analogues | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2005-08-18 | — | — | US | disclosed |
| EP-1268396-B1 | DIPHENYL ETHER COMPOUNDS USEFUL IN THERAPY | PFIZER LTD (GB) | 2005-07-20 | — | — | EP | disclosed |
| EP-1537065-A1 | ANALOGUES OF VITAMIN D | Galderma Research & Development, S.N.C. (FR) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004020379-A1 | ANALOGUES OF VITAMIN D | GALDERMA RESEARCH & DEVELOPMENT, SNC (FR) | 2004-03-11 | — | — | WO | disclosed |
| EP-1268396-A1 | DIPHENYL ETHER COMPOUNDS USEFUL IN THERAPY | Pfizer Limited (GB) | 2003-01-02 | — | — | EP | disclosed |
| US-6448293-B1 | TREATMENT OR PREVENTION OF A DISORDER IN WHICH THE REGULATION OF MONOAMINE TRANSPORTER FUNCTION IS IMPLICATED, SUCH AS PREMATURE EJACULATION. | PFIZER INC. | 2002-09-10 | — | — | US | disclosed |
| US-20020052395-A1 | Diphenyl ether compounds useful in therapy | ANDREWS MARK DAVID (GB) | 2002-05-02 | — | — | US | disclosed |
| WO-2001072687-A1 | DIPHENYL ETHER COMPOUNDS USEFUL IN THERAPY | PFIZER LIMITED (GB) | 2001-10-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288270-A1 | New aminopyridine derivatives and their use as pharmaceuticals | DRD2, DRD1, DRD3 | TSHR 2194/4885ALDH1A1 792/4885LMNA 4736/4885 |
| US-20050182144-A1 | Novel vitamin D analogues | CYP24A1, CYP2R1, VDR | TSHR 816/4885ALDH1A1 121/4885LMNA 3140/4885 |
| US-20200055850-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | DDT, ACHE, GSTM1 | TSHR 510/4885ALDH1A1 535/4885LMNA 4562/4885 |
| US-20020052395-A1 | Diphenyl ether compounds useful in therapy | CBR1, OGFR, CBR3 | TSHR 112/4885ALDH1A1 2048/4885LMNA 3251/4885 |
| US-20200207741-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | BTK, SYK, LYN | TSHR 3659/4885ALDH1A1 3660/4885LMNA 3704/4885 |
| US-10640491-B2 | Inhibitors of bruton's tyrosine kinase | BTK, SYK, LYN | TSHR 3754/4885ALDH1A1 3869/4885LMNA 4187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.