Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MGLL | Q99685 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | XBP1 | P17861 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803670 | 0.83 | TK1 (0.43) | TK1MAPK10MEN1KMT2AMGLL | |
| SCHEMBL5085666 | 0.77 | MAPK10 (0.44) | MAPK10MEN1KMT2AMAPK1TSHR | |
| SCHEMBL8952262 | 0.71 | MAPK1 (0.34) | MAPK1HPGDALDH1A1HSD17B10 | |
| SCHEMBL8687559 | 0.71 | MAPK10 (0.36) | MAPK10MEN1KMT2AMAPK1TSHR | |
| SCHEMBL6421931 | 0.70 | KDM1A (0.39) | MAPK10MEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL8952197 | 0.70 | HSD17B10 (0.34) | MAPK10MEN1KMT2AMAPK1HTT | |
| SCHEMBL8952275 | 0.70 | HSD17B10 (0.34) | MAPK10MEN1KMT2AMAPK1HTT | |
| SCHEMBL8952345 | 0.70 | HSD17B10 (0.34) | MAPK10MEN1KMT2AMAPK1HTT | |
| SCHEMBL6948264 | 0.68 | EPHX2 (0.37) | MAPK10HTTSMN1; SMN2HPGDLMNA | |
| SCHEMBL8803812 | 0.68 | HSD17B10 (0.34) | MAPK10MEN1KMT2AMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697873-A4 | — | — | 1996-04-03 | — | — | EP | disclosed |
| EP-0697873-A1 | OLEFIN-SUBSTITUTED LONG CHAIN COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1996-02-28 | — | — | EP | disclosed |
| WO-1994015606-A1 | OLEFIN-SUBSTITUTED LONG CHAIN COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-07-21 | — | — | WO | disclosed |