Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.53 |
| ▸ | LAP3 | P28838 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | PLAT | P00750 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953583 | 1.00 | LTA4H (0.53) | LTA4HLAP3F2PLAUPLAT | |
| SCHEMBL4219709 | 0.90 | ALDH1A1 (0.55) | LTA4HLAP3ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL7046944 | 0.90 | ALDH1A1 (0.55) | LTA4HLAP3ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL262278 | 0.90 | ALDH1A1 (0.55) | LTA4HLAP3ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL19088598 | 0.87 | LMNA (0.56) | LTA4HLAP3ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL23279460 | 0.84 | PPARG (0.52) | LTA4HLAP3ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL18256456 | 0.84 | LTA4H (0.50) | LTA4HLAP3ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL7228873 | 0.84 | PPARG (0.52) | LTA4HLAP3ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL18407490 | 0.84 | ALDH1A1 (0.50) | LTA4HLAP3ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL22502779 | 0.84 | ALDH1A1 (0.50) | LTA4HLAP3ALDH1A1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598293-B2 | Compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES, INC. (US) | 2009-10-06 | — | — | US | disclosed |
| US-7365064-B2 | Benzoxazine and benzothiazine derivatives and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES LIMITED (IN) | 2008-04-29 | — | — | US | disclosed |
| US-20070142470-A1 | COMPOUNDS AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LIMITED | 2007-06-21 | — | — | US | disclosed |
| CN-1061039-C | Cyclodepsipeptide compound | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | CN | disclosed |
| CN-1039331-C | Depsispeptide derivative, preparation and application of same | FUJISAMA PHARMACEUTICAL CO LTD (JP) | 1998-07-29 | — | — | CN | disclosed |
| CN-1133592-A | Cyclic Depsipeptide Compounds | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-10-16 | — | — | CN | disclosed |
| US-5514773-A | PARASITICIDES, ANTHELMINTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-07 | — | — | US | disclosed |
| CN-1080932-A | Depsipeptide derivative and manufacture method thereof and purposes | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-01-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142470-A1 | COMPOUNDS AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LIPA, PCSK9, GPR119 | LTA4H 1107/4885LAP3 1403/4885F2 1189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.