Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 5/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953781 | 0.79 | ALDH1A1 (0.43) | L3MBTL1KDM2BCCR2ALDH1A1KMT2A | |
| SCHEMBL28124115 | 0.77 | PARP1 (0.67) | KMT2APARP1FYN | |
| SCHEMBL9308093 | 0.77 | MRGPRX4 (0.51) | KDM2BALDH1A1 | |
| SCHEMBL3148484 | 0.75 | KMT2A (0.66) | KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL30442255 | 0.75 | MAOB (0.62) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL3151885 | 0.75 | MAOB (0.62) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL8953864 | 0.75 | MAOB (0.47) | KDM2BALDH1A1KMT2ARAB9A | |
| SCHEMBL8953796 | 0.74 | KMT2A (0.51) | KDM2BALDH1A1KMT2ARAB9A | |
| SCHEMBL3069825 | 0.74 | MRGPRX4 (0.56) | L3MBTL1ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL6356224 | 0.74 | KMT2A (0.47) | KMT2ARAB9ANPC1PARP1FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484786-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1996-01-16 | — | — | US | disclosed |