Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953811 | 0.86 | ALOX5 (0.40) | MAOBLMNARAB9ATSHRKMT2A | |
| SCHEMBL8953796 | 0.83 | KMT2A (0.51) | ALDH1A1KDM2BMAOBSMPD1MAOA | |
| SCHEMBL8953864 | 0.82 | MAOB (0.47) | ALDH1A1KDM2BMAOBSMPD1MAOA | |
| SCHEMBL8953659 | 0.81 | SIRT2 (0.38) | ALDH1A1LMNAHPGDRAB9ATSHR | |
| SCHEMBL9308093 | 0.78 | MRGPRX4 (0.51) | ALDH1A1KDM2BMAOBNR4A2 | |
| SCHEMBL9246947 | 0.77 | ALOX5 (0.62) | — | |
| SCHEMBL8953753 | 0.73 | L3MBTL1 (0.44) | ALDH1A1KDM2BHPGDRAB9AKMT2A | |
| SCHEMBL22717033 | 0.73 | NR4A2 (0.70) | ALDH1A1KDM2BMAOBSMPD1NR4A2 | |
| SCHEMBL8953777 | 0.72 | MAOB (0.43) | ALDH1A1KDM2BMAOBSMPD1MAOA | |
| SCHEMBL8953702 | 0.72 | MAOB (0.43) | ALDH1A1KDM2BMAOBSMPD1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484786-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1996-01-16 | — | — | US | disclosed |