SCHEMBL8954422

SCHEMBL8954422

Cc1csc([C@H](O)[C@@H](CO)NC(=O)O)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.39
LMNA P02545 2/20 0.35
TSHR P16473 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.33
MARS2 Q96GW9 1/20 0.33
CYP2C19 P33261 1/20 0.33
CXCR1 P25024 1/20 0.32
CXCR2 P25025 1/20 0.32
PSMB5 P28074 1/20 0.32
GAA P10253 1/20 0.30
RPLP1 P05386 1/20 0.30
RPLP0 P05388 1/20 0.30
RPS17 P08708 1/20 0.30
RPSA P08865 1/20 0.30
RPS2 P15880 1/20 0.30
RPL35A P18077 1/20 0.30
RPL7 P18124 1/20 0.30
RPL17 P18621 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9151978 0.90 LMNA (0.35) DAOLMNATSHRSMN1; SMN2ALDH1A1
SCHEMBL8370027 0.90 LMNA (0.35) DAOLMNATSHRSMN1; SMN2ALDH1A1
SCHEMBL8896392 0.88 LMNA (0.48) DAOLMNATSHRSMN1; SMN2ALDH1A1
SCHEMBL8370102 0.88 LMNA (0.48) DAOLMNATSHRSMN1; SMN2ALDH1A1
SCHEMBL8367398 0.85 HTT (0.40) LMNASMN1; SMN2ALDH1A1PSMB5
SCHEMBL10757032 0.82 LMNA (0.45) LMNAPSMB5
SCHEMBL10753703 0.82 LMNA (0.45) LMNAPSMB5
SCHEMBL10757714 0.77 ALDH1A1 (0.34) LMNATSHRALDH1A1CYP3A4CYP2C19
SCHEMBL10761215 0.75 BCHE (0.40) LMNAALDH1A1PSMB5
Hydrochloric Acid SCHEMBL10759457 0.74 ACP3 (0.36) LMNASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5556829-A AMIDES, SULFONAMIDES, PHOSPHOAMIDES, AGRICULTURAL USE ZAMBON GROUP S.P.A. (IT) 1996-09-17 US disclosed
EP-0454067-B1 Compositions having herbicidal activity containing N-Alkyl-amides as active ingredient ZAMBON SPA (IT) 1995-09-27 EP disclosed
US-5336664-A Compositions having herbicidal activity containing N-alkyl-amides as active ingredient ZAMBON GROUP S.P.A. (IT) 1994-08-09 US disclosed
EP-0454067-A1 Compositions having herbicidal activity containing N-Alkyl-amides as active ingredient ZAMBON GROUP S.p.A. (IT) 1991-10-30 EP disclosed