Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MARS2 | Q96GW9 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.41 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.41 |
| ▸ | RPS17 | P08708 | 1/20 | 0.41 |
| ▸ | RPSA | P08865 | 1/20 | 0.41 |
| ▸ | RPS2 | P15880 | 1/20 | 0.41 |
| ▸ | RPL35A | P18077 | 1/20 | 0.41 |
| ▸ | RPL7 | P18124 | 1/20 | 0.41 |
| ▸ | RPL17 | P18621 | 1/20 | 0.41 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.41 |
| ▸ | RPS3 | P23396 | 1/20 | 0.41 |
| ▸ | RPS12 | P25398 | 1/20 | 0.41 |
| ▸ | RPL13 | P26373 | 1/20 | 0.41 |
| ▸ | RPL10 | P27635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896392 | 1.00 | LMNA (0.48) | LMNATSHRCYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL8954422 | 0.88 | DAO (0.39) | LMNATSHRCYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL8370027 | 0.87 | LMNA (0.35) | LMNATSHRCYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL9151978 | 0.87 | LMNA (0.35) | LMNATSHRCYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL8367398 | 0.80 | HTT (0.40) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL10757032 | 0.77 | LMNA (0.45) | LMNA | |
| SCHEMBL1753533 | 0.75 | LMNA (0.70) | LMNATSHRCYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL10757714 | 0.72 | ALDH1A1 (0.34) | LMNATSHRCYP3A4ALDH1A1CYP2C19 | |
| SCHEMBL8589514 | 0.71 | TACR1 (0.34) | DAO | |
| SCHEMBL8589511 | 0.71 | TACR1 (0.34) | DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500177-B1 | Process for the preparation of trans-(5R)-2,4,5-trisubstituted 2-oxazolines | ZAMBON SPA (IT) | 1999-01-07 | — | — | EP | disclosed |
| EP-0500177-A1 | Process for the preparation of trans-(5R)-2,4,5-trisubstituted 2-oxazolines | ZAMBON GROUP S.p.A. (IT) | 1992-08-26 | — | — | EP | disclosed |