SCHEMBL8954641

SCHEMBL8954641

CCCCCCCCCCCCCCN(CCCCCCCCCCCCCC)C(C)CC(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 11/20 0.48
PPARD Q03181 8/20 0.43
PPARG P37231 7/20 0.43
PPARA Q07869 7/20 0.43
HDAC11 Q96DB2 5/20 0.43
TSHR P16473 4/20 0.43
PTPN1 P18031 3/20 0.43
ALDH1A1 P00352 2/20 0.43
TLR2 O60603 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
FABP4 P15090 2/20 0.43
SLC22A6 Q4U2R8 1/20 0.43
SLC22A8 Q8TCC7 1/20 0.43
MEN1 O00255 1/20 0.43
ESR1 P03372 1/20 0.43
ALOX15 P16050 1/20 0.43
PDE4A P27815 1/20 0.43
KMT2A Q03164 1/20 0.43
PDE3A Q14432 1/20 0.43
HSD17B10 Q99714 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8954721 1.00 GPR84 (0.48) GPR84PPARDPPARGPPARAHDAC11
SCHEMBL30863372 0.86 ALDH1A1 (0.56) PPARDPPARGPPARATSHRALDH1A1
SCHEMBL11587637 0.83 GPR84 (0.47) GPR84PPARDPPARGPPARAHDAC11
SCHEMBL11585199 0.83 GPR84 (0.47) GPR84PPARDPPARGPPARAHDAC11
SCHEMBL4856092 0.82 SIGMAR1 (0.50) TSHRALDH1A1TDP1MEN1ESR1
SCHEMBL2214034 0.79 GPR84 (0.47) GPR84PPARDPPARGPPARAHDAC11
SCHEMBL2283334 0.79 GPR84 (0.47) GPR84PPARDPPARGPPARAHDAC11
SCHEMBL9718424 0.79 GPR84 (0.47) GPR84PPARDPPARGPPARAHDAC11
SCHEMBL9442148 0.79 GPR84 (0.47) GPR84PPARDPPARGPPARAHDAC11
SCHEMBL15047639 0.79 GPR84 (0.47) GPR84PPARDPPARGPPARAHDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0323409-B1 Polyolefin compositions stabilized with long chain N,N-dialkylhydroxylamines CIBA GEIGY AG (CH) 1996-01-03 EP disclosed
EP-0323409-A2 Polyolefin compositions stabilized with long chain N,N-dialkylhydroxylamines CIBA-GEIGY AG (CH) 1989-07-05 EP disclosed