SCHEMBL2214034

SCHEMBL2214034

CCCCCCCCCCCCN(CCCCCCCCCCCC)[C@@H](CC(=O)O)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 12/20 0.47
NOD1 Q9Y239 2/20 0.46
PPARG P37231 7/20 0.42
PPARD Q03181 7/20 0.42
PPARA Q07869 7/20 0.42
HDAC11 Q96DB2 5/20 0.42
TSHR P16473 4/20 0.42
PTPN1 P18031 3/20 0.42
ALDH1A1 P00352 2/20 0.42
TLR2 O60603 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
FABP4 P15090 2/20 0.42
SLC22A6 Q4U2R8 1/20 0.42
SLC22A8 Q8TCC7 1/20 0.42
MEN1 O00255 1/20 0.42
ESR1 P03372 1/20 0.42
ALOX15 P16050 1/20 0.42
PDE4A P27815 1/20 0.42
KMT2A Q03164 1/20 0.42
PDE3A Q14432 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15047639 1.00 GPR84 (0.47) GPR84NOD1PPARGPPARDPPARA
SCHEMBL2213923 1.00 GPR84 (0.47) GPR84NOD1PPARGPPARDPPARA
SCHEMBL2283334 1.00 GPR84 (0.47) GPR84NOD1PPARGPPARDPPARA
SCHEMBL9718424 1.00 GPR84 (0.47) GPR84NOD1PPARGPPARDPPARA
SCHEMBL9442148 1.00 GPR84 (0.47) GPR84NOD1PPARGPPARDPPARA
SCHEMBL7567415 1.00 GPR84 (0.47) GPR84NOD1PPARGPPARDPPARA
Carbamic Acid SCHEMBL2289549 0.95 NOD1 (0.46) GPR84NOD1PPARGPPARDPPARA
SCHEMBL19852728 0.93 GPR84 (0.44) GPR84NOD1PPARGPPARDPPARA
SCHEMBL31321524 0.93 GPR84 (0.44) GPR84NOD1PPARGPPARDPPARA
Hydrochloric Acid SCHEMBL3914766 0.91 GPR84 (0.40) GPR84NOD1PPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180311316-A1 INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHOSE PI IS BETWEEN 5.8 AND 8.5 ADOCIA (FR) 2018-11-01 US claimed
US-20170182131-A9 INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHOSE PI IS BETWEEN 5.8 AND 8.5 ADOCIA (FR) 2017-06-29 US claimed
EP-2741765-B9 INJECTABLE SOLUTION OF AT LEAST ONE TYPE OF BASAL INSULIN ADOCIA (FR) 2016-09-28 EP claimed
EP-2741765-B1 INJECTABLE SOLUTION OF AT LEAST ONE TYPE OF BASAL INSULIN ADOCIA (FR) 2016-03-30 EP claimed
US-20150250858-A1 INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHOSE PI IS BETWEEN 5.8 AND 8.5 ADOCIA (FR) 2015-09-10 US claimed
US-9089476-B2 Injectable solution at pH 7 comprising at least one basal insulin whose PI is between 5.8 and 8.5 ADOCIA (FR) 2015-07-28 US claimed
US-20130065826-A1 Injectable solution at pH 7 Comprising at least one basal insulin whose PI is between 5.8 and 8.5 ADOCIA (FR) 2013-03-14 US claimed
US-20120309680-A1 Functionalized oligosaccharides ADOCIA (FR) 2012-12-06 US claimed
US-20230242475-A1 Compositions Containing Dialkyl Amino Acid Ester Salts STEPAN CO (US) 2023-08-03 US disclosed
EP-4211107-A1 COMPOSITIONS CONTAINING DIALKYL AMINO ACID ESTER SALTS Stepan Company (US) 2023-07-19 EP disclosed
WO-2022056366-A1 COMPOSITIONS CONTAINING DIALKYL AMINO ACID ESTER SALTS STEPAN COMPANY (US) 2022-03-17 WO disclosed
CN-113730555-A Injectable solution of basal insulin and substituted copoly (amino acid) having pH7 and at least PI 5.8 to 8.5 阿道恰公司 2021-12-03 CN disclosed
CN-109640953-B Injectable solutions comprising copolymerized amino acids with carboxylate charge and hydrophobic groups 阿道恰公司 2021-10-29 CN disclosed
CN-109379888-B Injectable solutions comprising copolymerized amino acids with carboxylate charge and hydrophobic groups 阿道恰公司 2021-10-29 CN disclosed
US-20130245246-A1 POLYSACCHARIDES COMPRISING CARBOXYL FUNCTIONAL GROUPS SUBSTITUTED BY A HYDROPHOBIC ALCOHOL DERIVATIVE ADOCIA (FR) 2013-09-19 US disclosed
US-20130178415-A1 Injectable solution at pH 7 comprising at least one basal insulin the PI of which is between 5.8 and 8.5 and a substituted co-polyamino acid ADOCIA (FR) 2013-07-11 US disclosed
US-20130065826-A1 Injectable solution at pH 7 Comprising at least one basal insulin whose PI is between 5.8 and 8.5 ADOCIA (FR) 2013-03-14 US disclosed
US-20120309680-A1 Functionalized oligosaccharides ADOCIA (FR) 2012-12-06 US disclosed
US-20110195913-A1 Anionic polysaccharides functionalized by at least two hydrophobic groups carried by an at least trivalent spacer ADOCIA (FR) 2011-08-11 US disclosed
US-20110178011-A1 Polysaccharide/BMP complexes which are soluble at physiological pH ADOCIA (FR) 2011-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170182131-A9 INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHOSE PI IS BETWEEN 5.8 AND 8.5 IAPP, IGFBP5, INSR GPR84 3987/4885NOD1 1075/4885PPARG 503/4885
US-20130245246-A1 POLYSACCHARIDES COMPRISING CARBOXYL FUNCTIONAL GROUPS SUBSTITUTED BY A HYDROPHOBIC ALCOHOL DERIVATIVE CD44, B3GAT3, UGCG GPR84 2444/4885NOD1 602/4885PPARG 350/4885
US-20180311316-A1 INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHOSE PI IS BETWEEN 5.8 AND 8.5 IAPP, IGFBP5, INSR GPR84 3987/4885NOD1 1075/4885PPARG 503/4885
US-20150250858-A1 INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHOSE PI IS BETWEEN 5.8 AND 8.5 IAPP, IGFBP5, INSR GPR84 3987/4885NOD1 1075/4885PPARG 503/4885
US-20110195913-A1 Anionic polysaccharides functionalized by at least two hydrophobic groups carried by an at least trivalent spacer CD44, CSGALNACT1, ALG1 GPR84 3376/4885NOD1 981/4885PPARG 2303/4885
US-20130178415-A1 Injectable solution at pH 7 comprising at least one basal insulin the PI of which is between 5.8 and 8.5 and a substituted co-polyamino acid IAPP, VIP, IGFBP1 GPR84 1243/4885NOD1 1669/4885PPARG 885/4885
US-20230242475-A1 Compositions Containing Dialkyl Amino Acid Ester Salts DGKA, MGLL, DGKG GPR84 289/4885NOD1 4879/4885PPARG 1232/4885
US-20120309680-A1 Functionalized oligosaccharides OSTC, STT3A, DDOST GPR84 1185/4885NOD1 595/4885PPARG 4647/4885
US-20130065826-A1 Injectable solution at pH 7 Comprising at least one basal insulin whose PI is between 5.8 and 8.5 IAPP, IGFBP5, INSR GPR84 3987/4885NOD1 1075/4885PPARG 503/4885
US-20110178011-A1 Polysaccharide/BMP complexes which are soluble at physiological pH BMP1, BMP2, BMP6 GPR84 2454/4885NOD1 648/4885PPARG 3883/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.