Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | PKLR | P30613 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8956272 | 0.87 | GAA (0.48) | MAPTGAANPSR1ITGB3ITGAV | |
| SCHEMBL8954826 | 0.81 | GAA (0.53) | MAPTGAANPSR1ITGB3ITGAV | |
| SCHEMBL8956082 | 0.73 | F10 (0.54) | MAPTGAANPSR1 | |
| Iodide SCHEMBL8955180 | 0.73 | F10 (0.53) | MAPTGAANPSR1 | |
| SCHEMBL8956282 | 0.70 | MAPK1 (0.40) | MAPTGAAPKLRCYP3A4MEN1 | |
| SCHEMBL8954662 | 0.68 | DPP7 (0.41) | GAAPKLRCYP3A4KMT2ACYP2D6 | |
| SCHEMBL12132459 | 0.65 | ALDH1A1 (0.58) | MAPTGAANPSR1MEN1KMT2A | |
| SCHEMBL8385403 | 0.64 | TP53 (0.58) | MAPTGAANPSR1ITGB3ITGAV | |
| SCHEMBL8650770 | 0.64 | TP53 (0.58) | MAPTGAANPSR1ITGB3ITGAV | |
| SCHEMBL5098994 | 0.64 | NTSR1 (0.58) | MAPTGAANPSR1ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5518735-A | ANTICOAGULANTS ADMINISTERED BY MOUTH | PENTAPHARM AG (CH) | 1996-05-21 | — | — | US | disclosed |