SCHEMBL8955207

SCHEMBL8955207

C=C(CC(=O)OCC(O)CC)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.37
DUSP3 P51452 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
LMNA P02545 1/20 0.37
MGAM O43451 1/20 0.34
GAA P10253 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
TET2 Q6N021 4/20 0.34
TET3 O43151 1/20 0.34
TET1 Q8NFU7 1/20 0.34
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
LPAR6 P43657 1/20 0.33
LPAR1 Q92633 1/20 0.33
LPAR4 Q99677 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2367987 0.86 KDM4E (0.37) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL8459386 0.84 KDM4E (0.36) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL20267562 0.84 KDM4E (0.45) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL15946182 0.82 MGAM (0.50) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL8199981 0.81 MAPT (0.44) MGAMGAASIMGAM2TET2
SCHEMBL2240017 0.79 TSHR (0.48) MGAMGAASIMGAM2TET2
SCHEMBL2522797 0.77 GPR88 (0.34) MGAMGAASIMGAM2ALOX15
SCHEMBL14787710 0.77 MGAM (0.44) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL16350387 0.77 MGAM (0.44) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL262251 0.77 GAA (0.61) KDM4EMEN1KMT2ALMNAMGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4900631-A COPOLYMER OF VINYL CHLORIDE, SULFUR, OR PHOSPHORUS CONTAINING COMPOUND AND HYDROXY CONTAINING COMPOUND NIPPON ZEON CO., LTD. (JP) 1990-02-13 US claimed
US-4851465-A VINYL CHLORIDE, SULFUR OR PHOSPHORUS ACID UNSATURATED MONOMER, HYDROXY-CONTAINING UNSATURATED MONOMER, MAGNETIC RECORDING MEDIA NIPPON ZEON CO., LTD. (JP) 1989-07-25 US claimed
EP-0568412-B1 Dual process thermal transfer imaging MINNESOTA MINING & MFG (US) 1996-01-03 EP disclosed
EP-0530963-B1 Dye receptor sheet for thermal dye transfer imaging MINNESOTA MINING & MFG (US) 1995-10-11 EP disclosed
EP-0568412-A1 Dual process thermal transfer imaging MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-11-03 EP disclosed
US-5232892-A With surface layer of vinyl chloride copolymer having hydroxyl, sulfonate and epoxy groups and controlled glass transition temperature, for image stability MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-08-03 US disclosed
US-5225392-A Dual process thermal transfer imaging MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-07-06 US disclosed
EP-0530963-A1 Dye receptor sheet for thermal dye transfer imaging MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-03-10 EP disclosed
US-4851465-A VINYL CHLORIDE, SULFUR OR PHOSPHORUS ACID UNSATURATED MONOMER, HYDROXY-CONTAINING UNSATURATED MONOMER, MAGNETIC RECORDING MEDIA NIPPON ZEON CO., LTD. (JP) 1989-07-25 US disclosed
US-4818781-A VINYL CHLORIDE COPOLYMER WITH UNSATURATED CARBOXYL AND HYDROXYL GROUP MONOMERS NIPPON ZEON CO., LTD. (JP) 1989-04-04 US disclosed