Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 4/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8778502 | 0.84 | TDP1 (0.54) | MRGPRX4CYP2C19TDP1ALDH1A1CYP1A2 | |
| SCHEMBL8955369 | 0.81 | TP53 (0.47) | MRGPRX4GPR84CYP2C19TDP1ALDH1A1 | |
| SCHEMBL7228434 | 0.80 | GPR84 (0.47) | MRGPRX4GPR84CYP2C19TDP1ALDH1A1 | |
| SCHEMBL11441977 | 0.79 | TP53 (0.49) | MRGPRX4GPR84CYP2C19TDP1ALDH1A1 | |
| SCHEMBL243080 | 0.78 | MRGPRX4 (0.41) | MRGPRX4GPR84CYP2C19TDP1ALDH1A1 | |
| SCHEMBL11450814 | 0.77 | TP53 (0.50) | MRGPRX4GPR84CYP2C19TDP1ALDH1A1 | |
| SCHEMBL12968231 | 0.77 | GLA (0.49) | GPR84CYP2C19TDP1ALDH1A1CYP1A2 | |
| SCHEMBL8778533 | 0.76 | MAPT (0.53) | CYP2C19TDP1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL8778628 | 0.76 | ALDH1A1 (0.54) | MRGPRX4CYP2C19ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL8748237 | 0.76 | L3MBTL1 (0.57) | CYP2C19TDP1ALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574355-B1 | Phosphinyloxy propanaminium inner salt derivatives | CIBA GEIGY AG (CH) | 1997-08-13 | — | — | EP | claimed |
| EP-0574355-A1 | Phosphinyloxy propanaminium inner salt derivatives | SANDOZ LTD. (CH) | 1993-12-15 | — | — | EP | claimed |