Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | F2R | P25116 | 2/20 | 0.41 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8955535 | 0.78 | MAPT (0.39) | MAPTGAAALDH1A1CA2LMNA | |
| Hydrochloric Acid SCHEMBL8742118 | 0.77 | F2R (0.39) | MAPTGAAALDH1A1KDM4EUSP2 | |
| SCHEMBL11143770 | 0.74 | GAA (0.54) | MAPTGAAHCAR3TTRPLA2G2A | |
| SCHEMBL28104480 | 0.74 | GPR35 (0.46) | MAPTGAAHCAR3ALDH1A1F2R | |
| SCHEMBL15412739 | 0.74 | HCAR3 (0.62) | MAPTGAAHCAR3ALDH1A1KDM4E | |
| SCHEMBL11845733 | 0.74 | CA2 (0.56) | MAPTGAAHCAR3ALDH1A1KDM4E | |
| SCHEMBL2741846 | 0.73 | CA2 (0.64) | MAPTGAAHCAR3ALDH1A1KDM4E | |
| SCHEMBL30780100 | 0.72 | TTR (0.56) | MAPTHCAR3TTRALDH1A1KDM4E | |
| SCHEMBL18993698 | 0.72 | GAA (0.51) | MAPTGAAHCAR3ALDH1A1KDM4E | |
| Hexane SCHEMBL29263834 | 0.71 | PLA2G2A (0.62) | MAPTALDH1A1TSHRPLA2G2ATPMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516805-A | 3,5-substituted aminobenzoylguanidines, their use as a medicament or diagnostic and medicament containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-05-14 | — | — | US | disclosed |