Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | LTA4H | P09960 | 4/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8955656 | 0.85 | LTA4H (0.60) | TDP1L3MBTL1LTA4HFAAHCYSLTR2 | |
| SCHEMBL767042 | 0.85 | TDP1 (0.62) | TDP1L3MBTL1LTA4HFAAHCYSLTR2 | |
| SCHEMBL27921658 | 0.84 | LMNA (0.59) | TDP1L3MBTL1TSHRPOLBNPSR1 | |
| SCHEMBL3267158 | 0.84 | TDP1 (0.51) | TDP1L3MBTL1LTA4HCYSLTR2CYSLTR1 | |
| SCHEMBL16334283 | 0.83 | FFAR4 (0.73) | TDP1L3MBTL1LTA4HFFAR4FAAH | |
| SCHEMBL8158473 | 0.83 | HTR1A (0.54) | TDP1L3MBTL1LTA4HKDM4EMAPT | |
| SCHEMBL29213722 | 0.82 | TDP1 (0.64) | TDP1NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL3268399 | 0.81 | JAK2 (0.53) | TDP1L3MBTL1LTA4HCYSLTR2CYSLTR1 | |
| SCHEMBL5491821 | 0.80 | LTA4H (0.62) | TDP1L3MBTL1LTA4HFAAHCYSLTR2 | |
| SCHEMBL8158041 | 0.80 | PPARG (0.58) | TDP1L3MBTL1LTA4HCYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064269-A | 4-[(4-Phenoxy and benzyl)-phenoxy]-butyric acid esters | CIBA-GEIGY CORPORATION (US) | 1977-12-20 | — | — | US | claimed |
| US-5516767-A | PRODRUG AS HYPOGLYCEMIC AGENT | SANDOZ LTD. (CH) | 1996-05-14 | — | — | US | disclosed |
| US-5412137-A | Hypoglycemic agents | SANDOZ LTD. (CH) | 1995-05-02 | — | — | US | disclosed |