SCHEMBL948906

SCHEMBL948906

C#Cc1cc(-c2ccccc2)ccc1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.57
ESR2 Q92731 5/20 0.52
KDM4E B2RXH2 2/20 0.52
MEN1 O00255 1/20 0.52
USP2 O75604 1/20 0.52
ALDH1A1 P00352 1/20 0.52
LMNA P02545 1/20 0.52
HSP90AA1 P07900 1/20 0.52
GAA P10253 1/20 0.52
MAPT P10636 1/20 0.52
HPGD P15428 1/20 0.52
ALOX15 P16050 1/20 0.52
ALOX12 P18054 1/20 0.52
HTT P42858 1/20 0.52
KMT2A Q03164 1/20 0.52
HSD17B10 Q99714 1/20 0.52
ACMSD Q8TDX5 3/20 0.48
HNF4A P41235 2/20 0.48
DHFR P00374 1/20 0.48
MCL1 Q07820 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11420886 0.89 APP (0.48) ALOX5ESR2KDM4EMEN1USP2
SCHEMBL11409765 0.86 ALOX5 (0.56) ALOX5ESR2MEN1KMT2AESR1
SCHEMBL3880437 0.80 ALOX5 (0.57) ALOX5ESR2KDM4EMEN1USP2
SCHEMBL1180219 0.79 ALDH1A1 (0.41) ALOX5ESR2KDM4EMEN1USP2
SCHEMBL8955706 0.78 APP (0.45) ALOX5ESR2KDM4EMEN1USP2
SCHEMBL28739756 0.78 NPC1 (0.42) ALOX5ESR2KDM4EMEN1USP2
SCHEMBL24055427 0.77 MAOA (0.54) ALOX5ESR2KDM4EMEN1USP2
SCHEMBL30787959 0.77 MAOA (0.54) ALOX5ESR2KDM4EMEN1USP2
SCHEMBL1095325 0.76 ACMSD (0.58) ACMSDHNF4ADHFRMCL1
SCHEMBL15775864 0.74 MCL1 (0.53) KDM4EALDH1A1LMNAGAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100519623-C Fluorinated aromatic polymer and use thereof ASAHI GLASS CO LTD (JP) 2009-07-29 CN claimed
EP-2266792-B1 ELECTRET AND ELECTROSTATIC INDUCTION CONVERSION DEVICE ASAHI GLASS CO LTD (JP) 2016-05-04 EP disclosed
US-8212433-B2 Electret and electrostatic induction conversion device ASAHI GLASS COMPANY, LIMITED (JP) 2012-07-03 US disclosed
US-20110012438-A1 ELECTRET AND ELECTROSTATIC INDUCTION CONVERSION DEVICE ASAHI GLASS COMPANY, LIMITED 2011-01-20 US disclosed
EP-2266792-A1 ELECTRET AND ELECTROSTATIC INDUCTION CONVERSION DEVICE Asahi Glass Company, Limited (JP) 2010-12-29 EP disclosed
CN-100519623-C Fluorinated aromatic polymer and use thereof ASAHI GLASS CO LTD (JP) 2009-07-29 CN disclosed
US-7049393-B2 Techniques for the preparation of highly fluorinated polyethers NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2006-05-23 US disclosed
US-20040198906-A1 Techniques for the preparation of highly fluorinated polyethers NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2004-10-07 US disclosed
CN-1525988-A Fluorinated aromatic polymer and use thereof ������������ʽ���� 2004-09-01 CN disclosed
WO-2003099907-A1 TECHNIQUES FOR THE PREPARATION OF HIGHLY FLUORINATED POLYETHERS NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2003-12-04 WO disclosed
US-4221895-A POLYESTER, POLYSULFONATE, OR POLYSULFINATE THE DOW CHEMICAL COMPANY (US) 1980-09-09 US disclosed