Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.79 |
| ▸ | LDHA | P00338 | 1/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 2/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2328730 | 0.98 | WDR5 (0.77) | WDR5LDHANR4A1NR4A2NR4A3 | |
| SCHEMBL895573 | 0.89 | WDR5 (1.00) | WDR5LDHANR4A1NR4A2NR4A3 | |
| SCHEMBL29721418 | 0.89 | WDR5 (1.00) | WDR5LDHANR4A1NR4A2NR4A3 | |
| SCHEMBL2328732 | 0.83 | WDR5 (0.54) | WDR5LDHANR4A1NR4A2NR4A3 | |
| SCHEMBL14225351 | 0.83 | WDR5 (0.79) | WDR5LDHANR4A1NR4A2NR4A3 | |
| SCHEMBL455943 | 0.81 | ALDH1A1 (0.56) | WDR5IDO1HPGDALDH1A1CYP1B1 | |
| SCHEMBL29418178 | 0.81 | ALDH1A1 (0.56) | WDR5IDO1HPGDALDH1A1CYP1B1 | |
| SCHEMBL2240626 | 0.80 | WDR5 (0.81) | WDR5LDHANR4A1NR4A2NR4A3 | |
| SCHEMBL23815788 | 0.79 | WDR5 (0.79) | WDR5LDHANR4A1NR4A2NR4A3 | |
| SCHEMBL31633516 | 0.79 | ALDH1A1 (0.54) | WDR5IDO1HPGDALDH1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110251393-A1 | HELICENE DERIVATIVE, AXIALLY ASYMMETRIC AMINO ACID, AMINE OR AMINOALCOHOL DERIVATIVE, PERYLENE DERIVATIVE OR SALT THEREOF, AND METHODS FOR PRODUCING SAME | KYOTO UNIVERSITY (JP) | 2011-10-13 | — | — | US | disclosed |
| US-20110251393-A1 | HELICENE DERIVATIVE, AXIALLY ASYMMETRIC AMINO ACID, AMINE OR AMINOALCOHOL DERIVATIVE, PERYLENE DERIVATIVE OR SALT THEREOF, AND METHODS FOR PRODUCING SAME | KYOTO UNIVERSITY (JP) | 2011-10-13 | — | — | US | disclosed |
| US-20110251393-A1 | HELICENE DERIVATIVE, AXIALLY ASYMMETRIC AMINO ACID, AMINE OR AMINOALCOHOL DERIVATIVE, PERYLENE DERIVATIVE OR SALT THEREOF, AND METHODS FOR PRODUCING SAME | KYOTO UNIVERSITY (JP) | 2011-10-13 | — | — | US | disclosed |
| EP-2357177-A1 | HELICENE DERIVATIVE, AXIALLY ASYMMETRIC AMINO ACID, AMINE OR AMINOALCOHOL DERIVATIVE, PERYLENE DERIVATIVE OR SALT THEREOF, AND METHODS FOR PRODUCING SAME | Kyoto University (JP) | 2011-08-17 | — | — | EP | disclosed |
| WO-2010047318-A1 | HELICENE DERIVATIVE, AXIALLY ASYMMETRIC AMINO ACID, AMINE OR AMINOALCOHOL DERIVATIVE, PERYLENE DERIVATIVE OR SALT THEREOF, AND METHODS FOR PRODUCING SAME | 国立大学法人京都大学 (JP) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010047318-A1 | HELICENE DERIVATIVE, AXIALLY ASYMMETRIC AMINO ACID, AMINE OR AMINOALCOHOL DERIVATIVE, PERYLENE DERIVATIVE OR SALT THEREOF, AND METHODS FOR PRODUCING SAME | 国立大学法人京都大学 (JP) | 2010-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251393-A1 | HELICENE DERIVATIVE, AXIALLY ASYMMETRIC AMINO ACID, AMINE OR AMINOALCOHOL DERIVATIVE, PERYLENE DERIVATIVE OR SALT THEREOF, AND METHODS FOR PRODUCING SAME | AADAT, AASDHPPT, AZI2 | WDR5 2191/4885LDHA 2387/4885NR4A1 2064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.