SCHEMBL895626

SCHEMBL895626

NNC(=O)c1ccc([N+](=O)[O-])cc1C(=O)NN

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.53
CYP3A4 P08684 2/20 0.53
CTSD P07339 1/20 0.53
ALOX15 P16050 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
KMT2A Q03164 4/20 0.51
MAPT P10636 4/20 0.50
KDM4E B2RXH2 2/20 0.50
GAA P10253 2/20 0.50
LMNA P02545 2/20 0.49
MITF O75030 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
MEN1 O00255 2/20 0.47
RORC P51449 2/20 0.47
TP53 P04637 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
PKM P14618 1/20 0.47
TSHR P16473 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2833356 0.89 ALDH1A1 (0.57) ALDH1A1CYP3A4CTSDALOX15TDP1
SCHEMBL11079448 0.89 KMT2A (0.49) ALDH1A1CYP3A4CTSDALOX15TDP1
Water SCHEMBL11071684 0.88 KMT2A (0.48) ALDH1A1CYP3A4CTSDALOX15TDP1
SCHEMBL1637466 0.86 F10 (0.59) ALDH1A1CYP3A4CTSDTDP1KMT2A
SCHEMBL1176899 0.86 CTSD (0.63) ALDH1A1CYP3A4CTSDALOX15TDP1
SCHEMBL2847286 0.86 ALDH1A1 (0.59) ALDH1A1CYP3A4CTSDALOX15TDP1
SCHEMBL8834690 0.85 L3MBTL1 (0.50) ALDH1A1CYP3A4CTSDALOX15TDP1
SCHEMBL8834685 0.85 L3MBTL1 (0.50) ALDH1A1CYP3A4CTSDALOX15TDP1
SCHEMBL9055143 0.85 LMNA (0.59) ALDH1A1CYP3A4CTSDTDP1KMT2A
SCHEMBL20065126 0.85 KMT2A (0.51) ALDH1A1CYP3A4CTSDALOX15TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115925713-B Diazamacrocyclic compound intermediate, and preparation method and application thereof 苏州百灵威超精细材料有限公司 2024-12-24 CN disclosed
CN-115557967-B 4-Nitrophthaloyl aza crown ether compound, preparation method and application 苏州百灵威超精细材料有限公司 2024-07-02 CN disclosed
CN-115925713-A Diazacyclocycle compound intermediate and preparation method and application thereof 苏州百灵威超精细材料有限公司 2023-04-07 CN disclosed
CN-115557967-A 4-nitrophthaloyl aza crown ether compound, preparation method and application thereof 苏州百灵威超精细材料有限公司 2023-01-03 CN disclosed
EP-2440034-A1 HIGH OIL CONTENT PLANTS Bayer BioScience N.V. (BE) 2012-04-18 EP disclosed
US-20120084883-A1 High Oil Content Plants BAYER CROPSCIENCE N.V. (BE) 2012-04-05 US disclosed
WO-2010142424-A1 HIGH OIL CONTENT PLANTS BAYER BIOSCIENCE N.V. (BE) 2010-12-16 WO disclosed