Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | GLS2 | Q9UI32 | 1/20 | 0.39 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.39 |
| ▸ | LPL | P06858 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | LTK | P29376 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | MST1R | Q04912 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8209251 | 0.77 | GSK3B (1.00) | GSK3BHDAC2GLSGLS2SLC6A11 | |
| SCHEMBL8209254 | 0.77 | GSK3B (1.00) | GSK3BHDAC2GLSGLS2SLC6A11 | |
| SCHEMBL8209256 | 0.77 | GSK3B (1.00) | GSK3BHDAC2GLSGLS2SLC6A11 | |
| SCHEMBL8971519 | 0.75 | LMNA (0.50) | MEN1KMT2AHPGD | |
| SCHEMBL8971511 | 0.75 | LMNA (0.50) | MEN1KMT2AHPGD | |
| SCHEMBL8971517 | 0.75 | LMNA (0.50) | MEN1KMT2AHPGD | |
| SCHEMBL8956418 | 0.72 | GSK3B (0.54) | GSK3BHDAC1MEN1KMT2AHPGD | |
| SCHEMBL5852 | 0.68 | HDAC2 (0.56) | GSK3BHDAC2LPLLIPGLTA4H | |
| SCHEMBL5873746 | 0.68 | SLC6A11 (0.52) | SLC6A11 | |
| SCHEMBL13790222 | 0.68 | HDAC2 (0.64) | GSK3BHDAC2LPLLIPGLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188130-B1 | Anti-cancer hydantoin compounds and methods | UNIVERSITY OF LOUISIANA AT MONROE (US) | 2012-05-29 | — | — | US | disclosed |