SCHEMBL8957670

SCHEMBL8957670

O=C(O)CCn1nnnc1[S]

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EGLN3 Q9H6Z9 1/20 0.44
HSD11B1 P28845 7/20 0.40
KMO O15229 5/20 0.40
MAPK1 P28482 1/20 0.40
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
CYP1A2 P05177 1/20 0.34
APEX1 P27695 1/20 0.33
KDM4C Q9H3R0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4609642 0.80 ALDH1A1 (0.47) HSD11B1MAPK1ALDH1A1HPGDCYP1A2
SCHEMBL28711074 0.77 MAPK1 (0.50) EGLN3HSD11B1KMOMAPK1ALDH1A1
SCHEMBL829121 0.77 EGLN3 (0.44) EGLN3HSD11B1KMOMAPK1ALDH1A1
SCHEMBL17153786 0.76 KMT2A (0.46) EGLN3HSD11B1KMOMAPK1ALDH1A1
SCHEMBL28706456 0.74 EGLN3 (0.41) EGLN3HSD11B1KMOMAPK1ALDH1A1
SCHEMBL9602798 0.74 EGLN3 (0.41) EGLN3HSD11B1KMOMAPK1ALDH1A1
SCHEMBL9331808 0.73 LMNA (0.43) EGLN3HSD11B1KMOMAPK1ALDH1A1
SCHEMBL9331809 0.73 KMT2A (0.67) EGLN3HSD11B1KMOMAPK1ALDH1A1
SCHEMBL28711298 0.72 NAALAD2 (0.43) EGLN3HSD11B1KMOMAPK1ALDH1A1
SCHEMBL8947202 0.70 HSD11B1 (0.76) EGLN3HSD11B1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0313083-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1996-01-10 EP disclosed
EP-0307927-B1 Silver halide color photosensitive material FUJI PHOTO FILM CO LTD (JP) 1994-06-22 EP disclosed
US-H1248-H SUPERIOR DESILVERING SPEED, GOOD COLOR REFORMING PROPERTIES AND MINIMUM IMAGE DENSITIES FUJI PHOTO FILM CO., LTD. (JP) 1993-11-02 US disclosed
EP-0295632-B1 SILVER HALIDE COLOR PHOTOGRAPHIC MATERIALS FUJI PHOTO FILM CO., LTD. (JP) 1993-03-03 EP disclosed
US-5112729-A Cyan coupler and an ultraviolet radiation absorber FUJI PHOTO FILM CO., LTD. (JP) 1992-05-12 US disclosed
US-5064750-A Naphthol amido coupler, bleaching bath of diamino propane teraacetato iron complex FUJI PHOTO FILM CO., LTD. (JP) 1991-11-12 US disclosed
US-4952690-A 6-substituted thia-aza compounds CIBA-GEIGY CORPORATION (US) 1990-08-28 US disclosed
US-4950764-A HERBICIDES, BACTERICIDES, ANALGESICS, ANTIINFLAMMATORY AGENT FUJI PHOTO FILM CO., LTD. (JP) 1990-08-21 US disclosed
US-4914206-A ANTIBIOTICS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1990-04-03 US disclosed
EP-0307927-A2 Silver halide color photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 1989-03-22 EP disclosed
US-4271295-A HALOGENATION STEP SHIONOGI & CO., LTD. (JP) 1981-06-02 US disclosed
EP-0025017-A1 Polyazathia compounds, process for their preparation, pharmaceutical preparations containing such compounds and use of the latter CIBA-GEIGY AG (CH) 1981-03-11 EP disclosed
EP-0022245-A2 Aminothiadiazolyl derivatives, process for their preparation, pharmaceutical compositions containing them;starting compounds and process for their preparation CIBA-GEIGY AG (CH) 1981-01-14 EP disclosed
US-4233216-A INTERMEDIATES FOR OXADETHIACEPHALOSPORINS SHIONOGI & CO., LTD. (JP) 1980-11-11 US disclosed
EP-0016900-A1 Intermediates in the preparation of cephalosporin derivatives, process for their preparation and use CIBA-GEIGY AG (CH) 1980-10-15 EP disclosed
EP-0016296-A1 Cephalosporin derivatives, process for their preparation, compositions containing them, and intermediates and their preparation CIBA-GEIGY AG (CH) 1980-10-01 EP disclosed
US-4220766-A FROM PENICILLINS SHIONOGI & CO., LTD. (JP) 1980-09-02 US disclosed
US-4183855-A INTERMEDIATES FOR PREPARATION OF THE BACTERICIDE, 1-OXADETHIA-CEPHALOSPORIN SHIONOGI & CO., LTD. (JP) 1980-01-15 US disclosed
EP-0003960-A1 6-Substituted thia-aza-compounds, their preparation and pharmaceutical compositions containing them CIBA-GEIGY AG (CH) 1979-09-19 EP disclosed
EP-0000500-A2 Cephalosprin derivatives, process for their preparation and pharmaceutical compositions containing them CIBA-GEIGY AG (CH) 1979-02-07 EP disclosed