Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8958180 | 0.83 | ALDH1A1 (0.44) | NPC1RAB9AALDH1A1KCNH2TP53 | |
| SCHEMBL27424795 | 0.80 | ALDH1A1 (0.47) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL27669800 | 0.77 | CRHBP (0.46) | MEN1KMT2AALDH1A1TSHRHTR2A | |
| SCHEMBL9564928 | 0.74 | ALDH1A1 (0.41) | MEN1KMT2ANPC1RAB9ANOX1 | |
| Potassium Ion SCHEMBL8957905 | 0.72 | NR1H2 (0.35) | KMT2AALDH1A1TSHRPOLBKDM4E | |
| SCHEMBL9821084 | 0.72 | ALDH1A1 (0.44) | MEN1KMT2ANPC1RAB9ANOX1 | |
| SCHEMBL1668024 | 0.71 | TP53 (0.53) | MEN1KMT2ANPC1RAB9ANOX1 | |
| Potassium Ion SCHEMBL8958393 | 0.70 | ALDH1A1 (0.41) | NPC1RAB9AALDH1A1TSHRLMNA | |
| Potassium Ion SCHEMBL8958222 | 0.70 | ALDH1A1 (0.41) | NPC1RAB9AALDH1A1TSHRLMNA | |
| SCHEMBL1818951 | 0.70 | KMT2A (0.35) | MEN1KMT2ANPC1RAB9ANOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535842-B1 | Benzofuranones | ZENECA LTD (GB) | 1996-01-10 | — | — | EP | disclosed |
| US-5389597-A | For dye diffusion thermal transfer printing | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-02-14 | — | — | US | disclosed |
| US-5268490-A | With indan-1,3-dione and aminobenzene ring | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-07 | — | — | US | disclosed |
| EP-0535842-A1 | Benzofuranones | ZENECA LIMITED (GB) | 1993-04-07 | — | — | EP | disclosed |