Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 4/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10428051 | 1.00 | NAAA (0.44) | NAAASIGMAR1EGFREPHX1ALDH1A1 | |
| SCHEMBL10428049 | 1.00 | NAAA (0.44) | NAAASIGMAR1EGFREPHX1ALDH1A1 | |
| SCHEMBL8958323 | 1.00 | NAAA (0.44) | NAAASIGMAR1EGFREPHX1ALDH1A1 | |
| SCHEMBL29506752 | 0.98 | NAAA (0.42) | NAAASIGMAR1EGFREPHX1ALDH1A1 | |
| SCHEMBL29775536 | 0.98 | NAAA (0.42) | NAAASIGMAR1EGFREPHX1ALDH1A1 | |
| SCHEMBL28454510 | 0.98 | NAAA (0.42) | NAAASIGMAR1EGFREPHX1ALDH1A1 | |
| SCHEMBL9738358 | 0.81 | NAAA (0.46) | NAAASIGMAR1EGFREPHX1ALDH1A1 | |
| SCHEMBL9193383 | 0.81 | CYP3A4 (0.48) | SIGMAR1EGFRALDH1A1HPGD | |
| SCHEMBL9193386 | 0.81 | CYP3A4 (0.48) | SIGMAR1EGFRALDH1A1HPGD | |
| Azobenzene SCHEMBL27937521 | 0.80 | ALDH1A1 (0.60) | NAAAALDH1A1HTTTSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523436-A | ARYL-ALKYL TRIAZENIDO TRANSITION METAL COMPLEXES; HIGH ACTIVATION ENERGY; CROSSLINKED POLYSILOXANES | WACKER-CHEMIE GMBH (DE) | 1996-06-04 | — | — | US | disclosed |
| EP-0602638-B1 | Catalysts for hydrosilylation reactions | WACKER CHEMIE GMBH (DE) | 1996-03-06 | — | — | EP | disclosed |
| EP-0636642-B1 | Transition metal complexes bound to organopolysiloxanes | WACKER CHEMIE GMBH (DE) | 1995-12-06 | — | — | EP | disclosed |
| US-5426200-A | Having a triazene, tetrazene, tetrazadiene, pentazadiene or triazene oxide ligand; hydrosilation catalysts activated by heat or light; stability; solubility | WACKER-CHEMIE GMBH (DE) | 1995-06-20 | — | — | US | disclosed |
| EP-0636642-A1 | Transition metal complexes bound to organopolysiloxanes | Wacker-Chemie GmbH (DE) | 1995-02-01 | — | — | EP | disclosed |
| EP-0602638-A1 | Catalysts for hydrosilylation reactions | Wacker-Chemie GmbH (DE) | 1994-06-22 | — | — | EP | disclosed |