Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 4/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808465 | 0.98 | SIGMAR1 (0.47) | NAAASIGMAR1EPHX1ALDH1A1HTT | |
| SCHEMBL10752254 | 0.84 | SIGMAR1 (0.38) | SIGMAR1ALDH1A1HTT | |
| SCHEMBL10428051 | 0.81 | NAAA (0.44) | NAAASIGMAR1EPHX1ALDH1A1HTT | |
| SCHEMBL8958331 | 0.81 | NAAA (0.44) | NAAASIGMAR1EPHX1ALDH1A1HTT | |
| SCHEMBL8958323 | 0.81 | NAAA (0.44) | NAAASIGMAR1EPHX1ALDH1A1HTT | |
| SCHEMBL10428049 | 0.81 | NAAA (0.44) | NAAASIGMAR1EPHX1ALDH1A1HTT | |
| SCHEMBL28454510 | 0.80 | NAAA (0.42) | NAAASIGMAR1EPHX1ALDH1A1HTT | |
| SCHEMBL29775536 | 0.80 | NAAA (0.42) | NAAASIGMAR1EPHX1ALDH1A1HTT | |
| SCHEMBL29506752 | 0.80 | NAAA (0.42) | NAAASIGMAR1EPHX1ALDH1A1HTT | |
| SCHEMBL9700634 | 0.75 | SIGMAR1 (0.41) | NAAASIGMAR1EPHX1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110941-A | Methods of producing 1H-pyraolo(5,1-c)-1,2,4-triazoles and pyrazole derivatives | FUJI PHOTO FILM CO., LTD. (JP) | 1992-05-05 | — | — | US | disclosed |