Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MRE11 | P49959 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8958734 | 0.91 | ADORA1 (0.37) | ADORA1ADORA2ALMNAGRM5TP53 | |
| SCHEMBL8872885 | 0.91 | MME (0.37) | ADORA1ADORA2ALMNATP53ALDH1A1 | |
| SCHEMBL8958543 | 0.88 | WNT3A (0.38) | ADORA1ADORA2ALMNAGRM5TP53 | |
| SCHEMBL8872477 | 0.84 | MME (0.36) | LMNATP53ALDH1A1HTTGAA | |
| SCHEMBL8873067 | 0.81 | MME (0.37) | ADORA1ADORA2ALMNATP53ALDH1A1 | |
| SCHEMBL8958497 | 0.80 | LMNA (0.36) | LMNAGRM5TP53XDHALDH1A1 | |
| SCHEMBL8873617 | 0.79 | MME (0.37) | ADORA1ADORA2AGRM5L3MBTL1 | |
| SCHEMBL8878811 | 0.79 | BDKRB1 (0.40) | — | |
| SCHEMBL8873500 | 0.78 | MME (0.38) | ADORA1ADORA2AGRM5TP53L3MBTL1 | |
| SCHEMBL8872016 | 0.76 | MME (0.37) | ADORA1ADORA2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559236-A | Intermediates for substituted biphenylmethylmidazopyridine angiotensin II antagonists | EISAI CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |