Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 4/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | MRE11 | P49959 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8873617 | 0.91 | MME (0.37) | ADORA1ADORA2AGLAGRM5L3MBTL1 | |
| SCHEMBL8958405 | 0.88 | ADORA1 (0.37) | WNT3AADORA1ADORA2AGRM5MRE11 | |
| SCHEMBL8958734 | 0.85 | ADORA1 (0.37) | WNT3AADORA1ADORA2AGRM5MRE11 | |
| SCHEMBL8872411 | 0.85 | MME (0.36) | GLAGRM5L3MBTL1 | |
| SCHEMBL8872016 | 0.82 | MME (0.37) | ADORA1ADORA2AGLAL3MBTL1 | |
| SCHEMBL8958388 | 0.81 | WNT3A (0.37) | WNT3AGRM5CD274XDHCYP19A1 | |
| SCHEMBL8877163 | 0.80 | BDKRB1 (0.42) | — | |
| SCHEMBL8872885 | 0.78 | MME (0.37) | ADORA1ADORA2AL3MBTL1LMNATP53 | |
| SCHEMBL8875663 | 0.77 | BDKRB1 (0.40) | ADORA1ADORA2AL3MBTL1 | |
| SCHEMBL9088594 | 0.77 | L3MBTL1 (0.39) | ADORA1ADORA2AL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559236-A | Intermediates for substituted biphenylmethylmidazopyridine angiotensin II antagonists | EISAI CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |