Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MRE11 | P49959 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8958405 | 0.91 | ADORA1 (0.37) | ADORA1ADORA2AGRM5LMNATP53 | |
| SCHEMBL8873067 | 0.91 | MME (0.37) | ADORA1ADORA2ALMNATP53ALDH1A1 | |
| SCHEMBL8958543 | 0.85 | WNT3A (0.38) | ADORA1ADORA2AGRM5LMNATP53 | |
| SCHEMBL8872452 | 0.84 | MME (0.36) | LMNATP53ALDH1A1HTTPPARG | |
| SCHEMBL8872885 | 0.81 | MME (0.37) | ADORA1ADORA2ALMNATP53ALDH1A1 | |
| SCHEMBL8958623 | 0.80 | LMNA (0.36) | GRM5LMNATP53XDHCYP1A2 | |
| SCHEMBL8872016 | 0.79 | MME (0.37) | ADORA1ADORA2APPARG | |
| SCHEMBL8873500 | 0.78 | MME (0.38) | ADORA1ADORA2AGRM5TP53PPARG | |
| SCHEMBL8873617 | 0.76 | MME (0.37) | ADORA1ADORA2AGRM5PPARG | |
| SCHEMBL8958731 | 0.76 | XDH (0.36) | GRM5XDHCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559236-A | Intermediates for substituted biphenylmethylmidazopyridine angiotensin II antagonists | EISAI CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |