Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | PDE8A | O60658 | 1/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.35 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 3/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8872592 | 0.89 | AGTR1 (0.50) | AGTR1AGTR2AKT1PPARGTLR7 | |
| SCHEMBL8872862 | 0.76 | AGTR1 (0.47) | AGTR1AGTR2PPARG | |
| SCHEMBL8873957 | 0.75 | AGTR1 (0.61) | AGTR1AGTR2PPARG | |
| SCHEMBL9016407 | 0.73 | ALDH1A1 (0.38) | AGTR1AGTR2CYP19A1PPARGKDM4E | |
| SCHEMBL8876882 | 0.73 | PPARG (0.49) | AGTR1AGTR2PPARG | |
| SCHEMBL8872236 | 0.73 | AGTR1 (0.69) | AGTR1AGTR2AKT1PPARG | |
| SCHEMBL8873176 | 0.72 | PPARG (0.60) | AGTR1AGTR2PPARG | |
| SCHEMBL8872697 | 0.72 | AGTR1 (0.52) | AGTR1AGTR2PPARG | |
| SCHEMBL8872422 | 0.71 | PPARG (0.53) | AGTR1AGTR2PPARG | |
| SCHEMBL8958505 | 0.69 | AGTR1 (0.81) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559236-A | Intermediates for substituted biphenylmethylmidazopyridine angiotensin II antagonists | EISAI CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |