Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8873723 | 0.88 | ESR2 (0.34) | LMNACYP1A2CYP2C19PPARGUSP30 | |
| SCHEMBL9016476 | 0.79 | ESR2 (0.36) | LMNANPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8872862 | 0.74 | AGTR1 (0.47) | PPARGAGTR1AGTR2DPP4 | |
| SCHEMBL8958457 | 0.73 | AGTR1 (0.45) | ALDH1A1HPGDMAPK1KDM4EHSD17B10 | |
| SCHEMBL8872253 | 0.73 | AGTR1 (0.43) | ALDH1A1HPGDMAPK1LMNACYP1A2 | |
| SCHEMBL9016501 | 0.73 | AGTR1 (0.37) | LMNACYP1A2CYP2C19AGTR1AGTR2 | |
| SCHEMBL9016540 | 0.71 | PPARG (0.39) | XDHNPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9016542 | 0.69 | PPARG (0.46) | SMN1; SMN2HSD17B10MEN1TSHRKMT2A | |
| SCHEMBL9016396 | 0.67 | APLNR (0.42) | MAPK1LMNAPPARGAGTR1AGTR2 | |
| SCHEMBL8872592 | 0.65 | AGTR1 (0.50) | PPARGAGTR1AGTR2DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554757-A | Process for the preparation of imidazopyridine derivatives, and intermediates therefore | EISAI CO., LTD. (JP) | 1996-09-10 | — | — | US | disclosed |