Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9782367 | 0.89 | ALDH1A1 (0.60) | MAPTNPC1MAPK1HTTALDH1A1 | |
| SCHEMBL8984147 | 0.87 | MAPT (0.54) | MAPTNPC1MAPK1HTTALDH1A1 | |
| SCHEMBL10175303 | 0.84 | HTT (0.59) | MAPTNPC1MAPK1HTTALDH1A1 | |
| SCHEMBL24038312 | 0.82 | CES2 (0.53) | MAPTNPC1MAPK1HTTALDH1A1 | |
| SCHEMBL11947080 | 0.82 | HTT (0.62) | MAPTNPC1MAPK1HTTALDH1A1 | |
| SCHEMBL6097936 | 0.82 | MAPT (0.49) | MAPTNPC1MAPK1HTTALDH1A1 | |
| SCHEMBL10877746 | 0.82 | MAPT (0.71) | MAPTNPC1MAPK1HTTALDH1A1 | |
| SCHEMBL11947058 | 0.81 | ALDH1A1 (0.59) | MAPTNPC1MAPK1HTTALDH1A1 | |
| SCHEMBL305558 | 0.81 | NPSR1 (0.60) | MAPTNPC1MAPK1HTTALDH1A1 | |
| SCHEMBL29356028 | 0.81 | NPSR1 (0.60) | MAPTNPC1MAPK1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510468-A | FOR DYEING NATURAL OR SYNTHETIC SUBSTRATES | BASF AKTIENGESELLSCHAFT (DE) | 1996-04-23 | — | — | US | disclosed |
| US-5380859-A | Couplers for preparing azo dyes | BASF AKTIENGESELLSCHAFT (DE) | 1995-01-10 | — | — | US | disclosed |
| US-5364972-A | Preparation of nitrobenzophenones, and a color-stable modification of a benzophenone-azopyridone dye | BASF AKTIENGESELLSCHAFT (DE) | 1994-11-15 | — | — | US | disclosed |
| EP-0572450-B1 | AZO DYES HAVING A DIAZO COMPONENT FROM THE AMINOBENZOPHENONE SERIES, AS WELL AS BISULPHONATED PYRIDONE COMPOUNDS | BASF AG (DE) | 1994-10-26 | — | — | EP | disclosed |
| EP-0572450-A1 | AZO DYES HAVING A DIAZO COMPONENT FROM THE AMINOBENZOPHENONE SERIES, AS WELL AS BISULPHONATED PYRIDONE COMPOUNDS. | BASF AG (DE) | 1993-12-08 | — | — | EP | disclosed |
| EP-0534314-A2 | Process for the preparation of nitrobenzophenones and also the colour-fast modification of a benzophenoneazopyridone dye | BASF Aktiengesellschaft (DE) | 1993-03-31 | — | — | EP | disclosed |
| WO-1992014791-A1 | AZO DYES HAVING A DIAZO COMPONENT FROM THE AMINOBENZOPHENONE SERIES, AS WELL AS BISULPHONATED PYRIDONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 1992-09-03 | — | — | WO | disclosed |