Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10952578 | 0.90 | ALDH1A1 (0.58) | MAPTNPC1MAPK1HTTALDH1A1 | |
| SCHEMBL7189766 | 0.89 | NPC1 (0.47) | MAPTNPC1MAPK1HTTALDH1A1 | |
| SCHEMBL31457279 | 0.89 | NPC1 (0.47) | MAPTNPC1MAPK1HTTALDH1A1 | |
| SCHEMBL9856886 | 0.88 | ALDH1A1 (0.62) | MAPTNPC1MAPK1HTTALDH1A1 | |
| SCHEMBL8958574 | 0.87 | MAPT (0.57) | MAPTNPC1MAPK1HTTALDH1A1 | |
| SCHEMBL9544691 | 0.83 | HTT (0.56) | MAPTNPC1MAPK1HTTALDH1A1 | |
| SCHEMBL29380078 | 0.83 | AKR1C3 (0.59) | MAPTNPC1MAPK1HTTALDH1A1 | |
| SCHEMBL50128 | 0.83 | AKR1C3 (0.59) | MAPTNPC1MAPK1HTTALDH1A1 | |
| SCHEMBL31369141 | 0.82 | LMNA (0.50) | NPC1HTTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL286054 | 0.82 | LMNA (0.50) | NPC1HTTALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0534314-B1 | Process for the preparation of nitrobenzophenones and also the colour-fast modification of a benzophenoneazopyridone dye | BASF AG (DE) | 1996-06-05 | — | — | EP | disclosed |
| US-5364972-A | Preparation of nitrobenzophenones, and a color-stable modification of a benzophenone-azopyridone dye | BASF AKTIENGESELLSCHAFT (DE) | 1994-11-15 | — | — | US | disclosed |
| EP-0534314-A2 | Process for the preparation of nitrobenzophenones and also the colour-fast modification of a benzophenoneazopyridone dye | BASF Aktiengesellschaft (DE) | 1993-03-31 | — | — | EP | disclosed |
| US-4431585-A | THIAZOLE AND THIOPHENE DYES; DIAZOTIZATION; COUPLING | CASSELLA AKTIENGESELLSCHAFT (DE) | 1984-02-14 | — | — | US | disclosed |
| US-4329283-A | DISPERSE DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1982-05-11 | — | — | US | disclosed |
| EP-0035671-A1 | Water-insoluble azo dyestuffs, methods for their preparation and their use in dyeing and printing synthetic hydrophobic fibre materials | CASSELLA Aktiengesellschaft (DE) | 1981-09-16 | — | — | EP | disclosed |