Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.33 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1013749 | 0.99 | GABRA1 (0.36) | KDM4EALDH1A1TDP1GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL56683 | 0.90 | KDM4E (0.33) | KDM4EALDH1A1TDP1GABRA1GABRB2 | |
| Water SCHEMBL9229151 | 0.89 | KDM4E (0.33) | KDM4EALDH1A1TDP1GABRA1GABRB2 | |
| SCHEMBL5360957 | 0.89 | GABRA1 (0.33) | KDM4EALDH1A1TDP1GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL11238931 | 0.82 | KDM4E (0.31) | KDM4EALDH1A1TDP1GABRA1GABRB2 | |
| SCHEMBL11863963 | 0.81 | GABRA1 (0.31) | GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL6662799 | 0.81 | KDM4E (0.36) | KDM4EALDH1A1TDP1GABRA1GABRB2 | |
| SCHEMBL25349713 | 0.79 | GABRA1 (0.35) | KDM4EALDH1A1TDP1GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL9724638 | 0.79 | MEN1 (0.40) | KDM4EALDH1A1TDP1SLC6A2SLC6A4 | |
| Water SCHEMBL27319269 | 0.76 | KDM4E (0.39) | KDM4EALDH1A1TDP1GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110880554-B | Equipment and method for coating precursor solution and surfactant step by step | 杭州纤纳光电科技有限公司 | 2023-04-07 | — | — | CN | claimed |
| US-8895084-B2 | Oral care composition containing extract of unoxidized Camellia | COLGATE-PALMOLIVE COMPANY (US) | 2014-11-25 | — | — | US | claimed |
| US-20230346651-A1 | SURFACTANT-FREE FOAMABLE ORAL CARE COMPOSITION | SHANDONG BENZHEN COSMETICS CO., LTD. (CN) | 2023-11-02 | — | — | US | disclosed |
| US-20230310282-A1 | SURFACTANT-FREE FOAMABLE ORAL CARE COMPOSITION | SHANDONG BENZHEN COSMETICS CO., LTD. (CN) | 2023-10-05 | — | — | US | disclosed |
| EP-4216922-A1 | SURFACTANT-FREE FOAMABLE ORAL CARE COMPOSITION | Shandong Benzhen Cosmetics Co., Ltd (CN) | 2023-08-02 | — | — | EP | disclosed |
| EP-4210665-A1 | SURFACTANT-FREE FOAMABLE ORAL CARE COMPOSITION | Shandong Benzhen Cosmetics Co., Ltd (CN) | 2023-07-19 | — | — | EP | disclosed |
| CN-115708793-A | A foamable oral care composition free of surfactants | 山东本真化妆品有限公司 | 2023-02-24 | — | — | CN | disclosed |
| CN-115245470-A | Oil-in-water emulsion and its use against infantile eczema | 山东本真化妆品有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-111920758-B | A foamable oral care composition free of surfactants | 山东本真化妆品有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-114760977-A | Oral care products and methods of use and manufacture thereof | 高露洁-棕榄公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-114466644-A | Oral care compositions and methods of use | 高露洁-棕榄公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-111032011-A | Oral care compositions and uses thereof | 高露洁-棕榄公司 | 2020-04-17 | — | — | CN | disclosed |
| CN-110835845-A | Antibacterial finishing agent, antibacterial fabric and preparation method thereof | 三河市安霸生物技术有限公司 | 2020-02-25 | — | — | CN | disclosed |
| EP-2781581-A1 | Composition and process for demulsifying oil/water emulsions | Shell Internationale Research Maatschappij B.V. (NL) | 2014-09-24 | — | — | EP | disclosed |
| EP-2781582-A1 | Composition and process for demulsifying oil/water emulsions | Shell Internationale Research Maatschappij B.V. (NL) | 2014-09-24 | — | — | EP | disclosed |
| EP-2738235-A1 | Composition and process for demulsifying oil/water emulsions | Shell Internationale Research Maatschappij B.V. (NL) | 2014-06-04 | — | — | EP | disclosed |
| EP-2738234-A1 | Composition and process for demulsifying oil/water emulsions | Shell Internationale Research Maatschappij B.V. (NL) | 2014-06-04 | — | — | EP | disclosed |
| US-5508778-A | Processing machine for photographic elements | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-04-16 | — | — | US | disclosed |
| EP-0692736-A1 | Processing machine for photographic elements | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-01-17 | — | — | EP | disclosed |
| US-4926190-A | EMULSIONS | CIBA-GEIGY CORPORATION (US) | 1990-05-15 | — | — | US | disclosed |