Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 3/20 | 0.32 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.32 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25349713 | 0.99 | GABRA1 (0.35) | KDM4EALDH1A1TDP1MAOAMAOB | |
| Hydrochloric Acid SCHEMBL56683 | 0.91 | KDM4E (0.33) | KDM4EALDH1A1TDP1MAOAMAOB | |
| Water SCHEMBL9229151 | 0.90 | KDM4E (0.33) | KDM4EALDH1A1TDP1MAOAMAOB | |
| SCHEMBL5360957 | 0.90 | GABRA1 (0.33) | KDM4EALDH1A1TDP1MAOAGABRA1 | |
| Hydrochloric Acid SCHEMBL252557 | 0.82 | MEN1 (0.45) | MEN1KMT2ATP53MAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3695293 | 0.81 | ACHE (0.36) | GABRA1GABRB2SLC6A2SLC6A4KCNH2 | |
| SCHEMBL6524582 | 0.81 | DNM1 (0.44) | MEN1KMT2ATP53MAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8958601 | 0.81 | KDM4E (0.37) | KDM4EALDH1A1TDP1MAOAMAOB | |
| Hydrochloric Acid SCHEMBL11139244 | 0.79 | KDM4E (0.43) | KDM4EALDH1A1TDP1MAOASLC6A2 | |
| SCHEMBL1013749 | 0.79 | GABRA1 (0.36) | KDM4EALDH1A1TDP1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3648733-B1 | TOPICAL COMPOSITIONS | DSM IP ASSETS BV (NL) | 2025-08-06 | — | — | EP | disclosed |
| EP-3709954-B1 | TOPICAL COMPOSITIONS OF PHYTANTRIOL AND P-HYDROXYACETOPHENONE | DSM IP ASSETS BV (NL) | 2025-02-26 | — | — | EP | disclosed |
| EP-3965721-B1 | TOPICAL COMPOSITIONS WITH ANTIMICROBIAL AGENT MIXTURE | DSM IP ASSETS BV (NL) | 2023-06-14 | — | — | EP | disclosed |
| US-20220296480-A1 | TOPICAL COMPOSITIONS | DSM IP ASSETS B.V. (NL) | 2022-09-22 | — | — | US | disclosed |
| US-20220211594-A1 | TOPICAL COMPOSITIONS | DSM IP ASSETS B.V. (NL) | 2022-07-07 | — | — | US | disclosed |
| US-11364208-B2 | Topical compositions | DSM IP ASSETS B.V. (NL) | 2022-06-21 | — | — | US | disclosed |
| US-11324680-B2 | Topical compositions | DSM IP ASSETS B.V. (NL) | 2022-05-10 | — | — | US | disclosed |
| US-11306054-B2 | Propanediol monoacetate mononitrate | DSM IP ASSETS B.V. (NL) | 2022-04-19 | — | — | US | disclosed |
| EP-3965721-A1 | TOPICAL COMPOSITIONS | DSM IP Assets B.V. (NL) | 2022-03-16 | — | — | EP | disclosed |
| US-11191772-B2 | Use | DSM IP ASSETS B.V. (NL) | 2021-12-07 | — | — | US | disclosed |
| WO-2019007789-A1 | TOPICAL COMPOSITIONS | DSM IP ASSETS B.V. (NL) | 2019-01-10 | — | — | WO | disclosed |
| WO-2019007792-A1 | TOPICAL COMPOSITIONS | DSM IP ASSETS B.V. (NL) | 2019-01-10 | — | — | WO | disclosed |
| WO-2019007790-A1 | NOVEL USE | DSM IP ASSETS B.V. (NL) | 2019-01-10 | — | — | WO | disclosed |
| WO-2019007791-A1 | TOPICAL COMPOSITIONS | DSM IP ASSETS B.V. (NL) | 2019-01-10 | — | — | WO | disclosed |
| US-9980889-B2 | Compositions comprising P-hydroxybenzylamine | DSM IP ASSETS B.V. (NL) | 2018-05-29 | — | — | US | disclosed |
| US-20170035668-A1 | NOVEL COMPOSITIONS COMPRISING P-HYDROXYBENZYLAMINE | DSM IP ASSETS BV (NL) | 2017-02-09 | — | — | US | disclosed |
| US-20150208650-A1 | NOVEL COMPOSITIONS COMPRISING P-HYDROXYBENZYLAMINE | DSM IP ASSETS B.V. (NL) | 2015-07-30 | — | — | US | disclosed |
| EP-1439751-A1 | ANTIMICROBIALLY-TREATED FABRICS | Kimberly-Clark Worldwide, Inc. (US) | 2004-07-28 | — | — | EP | disclosed |
| WO-2003032726-A1 | ANTIMICROBIALLY-TREATED FABRICS | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2003-04-24 | — | — | WO | disclosed |
| EP-0102695-B1 | IMPROVED DENTIFRICE PREPARATIONS COMPRISING CALCINED KAOLIN ABRASIVES | INDIANA UNIVERSITY FOUNDATION (US) | 1990-04-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11306054-B2 | Propanediol monoacetate mononitrate | DERA, PHGDH, PGD | SLC6A2 3178/4885SLC6A3 2707/4885CHRM2 4278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.