Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.31 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9229151 | 0.99 | KDM4E (0.33) | KDM4EALDH1A1TDP1GABRA1GABRB2 | |
| SCHEMBL5360957 | 0.99 | GABRA1 (0.33) | KDM4EALDH1A1TDP1GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL6662799 | 0.91 | KDM4E (0.36) | KDM4EALDH1A1TDP1GABRA1GABRB2 | |
| SCHEMBL25349713 | 0.90 | GABRA1 (0.35) | KDM4EALDH1A1TDP1GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL8958601 | 0.90 | KDM4E (0.37) | KDM4EALDH1A1TDP1GABRA1GABRB2 | |
| SCHEMBL1013749 | 0.89 | GABRA1 (0.36) | KDM4EALDH1A1TDP1GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL1843352 | 0.82 | ACHE (0.32) | GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL11142161 | 0.80 | GABRA1 (0.32) | ALDH1A1GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL11238931 | 0.78 | KDM4E (0.31) | KDM4EALDH1A1TDP1GABRA1GABRB2 | |
| SCHEMBL11863963 | 0.77 | GABRA1 (0.31) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109312218-B | Determining residual friction reducer concentration for subterranean treatment fluids | 哈利伯顿能源服务公司 | 2021-08-31 | — | — | CN | claimed |
| US-20110245784-A1 | ANTI-INFECTIVE COMPOSITIONS, METHODS AND SYSTEMS FOR TREATING PATHOGEN-INDUCED DISORDERED TISSUES | QUADEX PHARMACEUTICALS, LLC (US) | 2011-10-06 | — | — | US | claimed |
| EP-2313026-A1 | ACTIVE DELIVERY SYSTEM FORMULATIONS | Castle Beach, L.L.C. (US) | 2011-04-27 | — | — | EP | claimed |
| WO-2010019680-A1 | ACTIVE DELIVERY SYSTEM FORMULATIONS | HOMOLA ANDREW M (US) | 2010-02-18 | — | — | WO | claimed |
| US-20100040565-A1 | ACTIVE DELIVERY SYSTEMS FORMULATIONS | Castle Beach, LLC (US) | 2010-02-18 | — | — | US | claimed |
| EP-0805672-B1 | METHODS, COMPOSITIONS, AND DENTAL DELIVERY SYSTEMS FOR THE PROTECTION OF THE SURFACES OF TEETH | HOMOLA ANDREW M (US) | 2004-08-25 | — | — | EP | claimed |
| US-5665333-A | Methods, compositions, and dental delivery systems for the protection of the surfaces of teeth | PROVSEAL LLC | 1997-09-09 | — | — | US | claimed |
| US-11633341-B2 | Dental varnishes that release specifically targeted antimicrobial peptides and/or fluoride | C3 JIAN, LLC (US) | 2023-04-25 | — | — | US | disclosed |
| US-11628136-B2 | Oral care compositions comprising at least one phosphate/acrylate copolymer and at least one cationic active ingredient | COLGATE-PALMOLIVE COMPANY (US) | 2023-04-18 | — | — | US | disclosed |
| CN-115362247-A | Aqueous laundry treatment composition | 联合利华知识产权控股有限公司 | 2022-11-18 | — | — | CN | disclosed |
| CN-109789384-B | Improvements in or relating to organic compounds | 奇华顿股份有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-113557038-A | Improved method and composition for surface treatment | 史蒂文·克里茨勒 | 2021-10-26 | — | — | CN | disclosed |
| CN-108472617-B | Microcapsules comprising a polyester-urethane shell and a hydrophilic core material | 巴斯夫欧洲公司 | 2021-09-14 | — | — | CN | disclosed |
| US-3946108-A | CLARITY, DEGASSING, SUSPENDING AIR OR NITROGEN BUBBLES | COLGATE-PALMOLIVE COMPANY (US) | 1976-03-23 | — | — | US | disclosed |
| US-3944661-A | MOTHER OF PEARL | COLGATE-PALMOLIVE COMPANY (US) | 1976-03-16 | — | — | US | disclosed |
| US-3943240-A | Toothpaste | COLGATE-PALMOLIVE COMPANY (US) | 1976-03-09 | — | — | US | disclosed |
| US-3937805-A | METHOD OF MAKING DENTIFRICE COMPOSITIONS CONTAINING INSOLUBILIZED SALTS OF 1,6-DI-(P-CHLOROPHENYL BIGUANIDO) HEXANE | COLGATE-PALMOLIVE COMPANY (US) | 1976-02-10 | — | — | US | disclosed |
| US-3937321-A | Toothpaste | COLGATE-PALMOLIVE COMPANY (US) | 1976-02-10 | — | — | US | disclosed |
| US-3937804-A | TOOTHPASTE | COLGATE-PALMOLIVE COMPANY (US) | 1976-02-10 | — | — | US | disclosed |
| US-3934000-A | SODIUM CARBOXYMETHYL CELLULOSE, POLYOXYETHYLENE GLYCOL, SILICA, ABRASIVE | COLGATE-PALMOLIVE COMPANY (US) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100040565-A1 | ACTIVE DELIVERY SYSTEMS FORMULATIONS | LIPA, MMP7, CTSA | KDM4E 4420/4885ALDH1A1 1412/4885TDP1 2046/4885 |
| US-11628136-B2 | Oral care compositions comprising at least one phosphate/acrylate copolymer and at least one cationic active ingredient | HDAC1, SLC30A5, HDAC11 | KDM4E 4575/4885ALDH1A1 1847/4885TDP1 1990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.