Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 7/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | RHEB | Q15382 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | STK10 | O94804 | 1/20 | 0.36 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | CTSV | O60911 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922549 | 0.70 | RHEB (0.42) | PPOXL3MBTL1RHEBMAPK14KMO | |
| SCHEMBL8926019 | 0.67 | PPOX (0.40) | PPOXL3MBTL1RHEBMAPK14KMO | |
| SCHEMBL8924085 | 0.66 | BCAT1 (0.58) | — | |
| SCHEMBL9652927 | 0.66 | PPOX (0.45) | PPOXL3MBTL1RHEBKMOAKR1B1 | |
| SCHEMBL9118892 | 0.66 | PPOX (0.43) | PPOXL3MBTL1MAPK14KMOAKR1B1 | |
| SCHEMBL810931 | 0.64 | MGAM (0.47) | L3MBTL1RHEBMAPK14NPC1RAB9A | |
| SCHEMBL31442635 | 0.64 | MGAM (0.47) | L3MBTL1RHEBMAPK14NPC1RAB9A | |
| SCHEMBL31442504 | 0.62 | PTGES (0.54) | CTSVCTSLNPC1MAPTRAB9A | |
| SCHEMBL810879 | 0.62 | PTGES (0.54) | CTSVCTSLNPC1MAPTRAB9A | |
| SCHEMBL18587382 | 0.62 | MAPT (0.49) | L3MBTL1MAPK14NPC1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5567670-A | TETRAHYDROTRIAZINE-DIONE DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-10-22 | — | — | US | disclosed |