SCHEMBL8958910

SCHEMBL8958910

NCCOc1ccc(Oc2cccc(Cl)c2)cc1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.46
PLA2G2A P14555 1/20 0.46
MRGPRX4 Q96LA9 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
GLA P06280 1/20 0.43
PPARD Q03181 3/20 0.42
PPARA Q07869 1/20 0.42
PPARG P37231 2/20 0.42
FFAR1 O14842 1/20 0.42
WDR5 P61964 1/20 0.41
MAOB P27338 3/20 0.40
CSNK2A1 P68400 1/20 0.40
LMNA P02545 1/20 0.40
MAPK1 P28482 1/20 0.40
HTT P42858 1/20 0.40
SLC6A4 P31645 2/20 0.40
SCN5A Q14524 1/20 0.40
SCN9A Q15858 1/20 0.40
AOC3 Q16853 1/20 0.40
SLC6A2 P23975 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8959117 0.88 LTA4H (0.62) LTA4HPLA2G2ASMN1; SMN2GLAPPARD
SCHEMBL8959091 0.86 LTA4H (0.46) LTA4HPLA2G2AMRGPRX4SMN1; SMN2GLA
SCHEMBL8958978 0.86 L3MBTL1 (0.49) LTA4HPLA2G2ASMN1; SMN2GLAPPARD
SCHEMBL8959054 0.86 LTA4H (0.44) LTA4HPLA2G2ASMN1; SMN2GLAPPARD
SCHEMBL8959126 0.86 PPARA (0.48) LTA4HPLA2G2ASMN1; SMN2GLAPPARD
SCHEMBL8658206 0.85 PPARD (0.45) MRGPRX4PPARDPPARAPPARGFFAR1
SCHEMBL8966908 0.84 LTA4H (0.66) LTA4HPLA2G2ASMN1; SMN2PPARDPPARG
SCHEMBL9459506 0.84 PPARD (0.44) MRGPRX4SMN1; SMN2PPARDPPARAPPARG
SCHEMBL8959081 0.82 PPARA (0.51) LTA4HPLA2G2AMRGPRX4PPARDPPARA
SCHEMBL8959084 0.81 PPARA (0.56) LTA4HPLA2G2ASMN1; SMN2GLAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0514833-B1 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL CO (JP) 1996-01-17 EP disclosed
EP-0460472-B1 Carbamic acid derivatives, their production and use SUMITOMO CHEMICAL CO (JP) 1995-03-08 EP disclosed
US-5364966-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-11-15 US disclosed
US-5356930-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-10-18 US disclosed
US-5346920-A Insecticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-09-13 US disclosed
EP-0514833-A2 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-11-25 EP disclosed
EP-0460472-A1 Carbamic acid derivatives, their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-12-11 EP disclosed