Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.66 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.66 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | WDR5 | P61964 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3167075 | 0.88 | LMNA (0.59) | LTA4HPLA2G2ATAAR1DRD2DRD4 | |
| SCHEMBL8958910 | 0.84 | LTA4H (0.46) | LTA4HPLA2G2AMAOBLMNAMAPK1 | |
| SCHEMBL10876902 | 0.83 | ALDH1A1 (0.53) | LTA4HPLA2G2ADRD2DRD4LMNA | |
| SCHEMBL10715309 | 0.82 | MAPT (0.54) | LTA4HMAOBSMN1; SMN2SCN5ASCN9A | |
| SCHEMBL507152 | 0.81 | ST14 (0.62) | TAAR1MAOBSMN1; SMN2SCN5ASCN9A | |
| Hydrochloric Acid SCHEMBL11429261 | 0.80 | LTA4H (0.66) | LTA4HPLA2G2ATAAR1MAOBLMNA | |
| SCHEMBL9511199 | 0.80 | LTA4H (0.66) | LTA4HPLA2G2ATAAR1MAOBSMN1; SMN2 | |
| SCHEMBL1048214 | 0.80 | MAOB (0.61) | TAAR1MAOBSMN1; SMN2KMT2A | |
| SCHEMBL9488010 | 0.80 | LTA4H (0.66) | LTA4HPLA2G2ATAAR1DRD2DRD4 | |
| SCHEMBL4653229 | 0.80 | LTA4H (1.00) | LTA4HPLA2G2ATAAR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0404720-B1 | Pesticidal agent | CIBA GEIGY AG (CH) | 1996-02-28 | — | — | EP | claimed |
| US-20100113513-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-05-06 | — | — | US | disclosed |
| US-20100113513-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-05-06 | — | — | US | disclosed |
| WO-2008110355-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-09-18 | — | — | WO | disclosed |
| US-5141956-A | Agricultural insecticides | CIBA-GEIGY CORPORATION (US) | 1992-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113513-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | CYP1A1, CYP4X1, CYP3A7 | LTA4H 2656/4885PLA2G2A 3789/4885TAAR1 1351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.