SCHEMBL8958978

SCHEMBL8958978

Cc1cccc(Oc2ccc(OCCN)c(Cl)c2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 8/20 0.49
ALDH1A1 P00352 3/20 0.49
MAPT P10636 5/20 0.45
RAB9A P51151 4/20 0.45
HPGD P15428 4/20 0.45
NPC1 O15118 2/20 0.45
ATM Q13315 1/20 0.45
LTA4H P09960 1/20 0.44
PLA2G2A P14555 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
GLA P06280 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
PPARD Q03181 1/20 0.43
PPARA Q07869 1/20 0.43
GAA P10253 2/20 0.43
CSNK2A1 P68400 2/20 0.41
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8958910 0.86 LTA4H (0.46) LTA4HPLA2G2ASMN1; SMN2GLAPPARD
SCHEMBL8959117 0.85 LTA4H (0.62) LTA4HPLA2G2ASMN1; SMN2GLAPPARD
SCHEMBL8959126 0.83 PPARA (0.48) LTA4HPLA2G2ASMN1; SMN2GLAPPARD
SCHEMBL8959054 0.83 LTA4H (0.44) ALDH1A1MAPTHPGDLTA4HPLA2G2A
SCHEMBL9488010 0.82 LTA4H (0.66) L3MBTL1ALDH1A1LTA4HPLA2G2ASMN1; SMN2
SCHEMBL8959091 0.81 LTA4H (0.46) ALDH1A1MAPTHPGDLTA4HPLA2G2A
SCHEMBL8958987 0.81 AR (0.53) L3MBTL1MAPTRAB9AHPGDNPC1
SCHEMBL18924248 0.80 MAPT (0.59) L3MBTL1ALDH1A1MAPTRAB9AHPGD
SCHEMBL8959081 0.80 PPARA (0.51) LTA4HPLA2G2APPARDPPARAPPARG
SCHEMBL9468315 0.78 L3MBTL1 (0.50) L3MBTL1ALDH1A1MAPTSMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0514833-B1 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL CO (JP) 1996-01-17 EP disclosed
EP-0460472-B1 Carbamic acid derivatives, their production and use SUMITOMO CHEMICAL CO (JP) 1995-03-08 EP disclosed
US-5364966-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-11-15 US disclosed
US-5356930-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-10-18 US disclosed
US-5346920-A Insecticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-09-13 US disclosed
EP-0514833-A2 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-11-25 EP disclosed
EP-0460472-A1 Carbamic acid derivatives, their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-12-11 EP disclosed