Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | AGXT | P21549 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | PGK1 | P00558 | 2/20 | 0.40 |
| ▸ | PGK2 | P07205 | 2/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29938481 | 0.85 | IDO1 (0.43) | IDO1AGXTMAOBLMNAGLA | |
| SCHEMBL4542812 | 0.85 | IDO1 (0.43) | IDO1AGXTMAOBLMNAGLA | |
| SCHEMBL4990445 | 0.83 | VNN1 (0.40) | MAOBRIPK1LMNAGLAHCAR2 | |
| SCHEMBL8959089 | 0.82 | IDO1 (0.43) | IDO1MAOBACP3LMNATAAR1 | |
| SCHEMBL6878860 | 0.81 | IDO1 (0.42) | IDO1AGXTMAOBRIPK1LMNA | |
| SCHEMBL8956972 | 0.80 | ACP3 (0.68) | IDO1MAOBACP3LMNATAAR1 | |
| SCHEMBL894078 | 0.80 | ALDH1A1 (0.44) | LMNA | |
| SCHEMBL28437720 | 0.79 | MMP13 (0.48) | IDO1AGXTLMNATAAR1 | |
| SCHEMBL8824671 | 0.79 | ACP3 (0.61) | IDO1AGXTACP3TAAR1PGK1 | |
| SCHEMBL915800 | 0.79 | TSHR (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500417-A | ANTIARTHRITIC | THE UPJOHN COMPANY (US) | 1996-03-19 | — | — | US | claimed |
| EP-0661978-A1 | ARYLMETHYLPHOSPHONATES AND PHOSPHONIC ACIDS USEFUL AS ANTI-INFLAMMATORY AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1995-07-12 | — | — | EP | claimed |
| WO-1994007501-A1 | ARYLMETHYLPHOSPHONATES AND PHOSPHONIC ACIDS USEFUL AS ANTI-INFLAMMATORY AGENTS | THE UPJOHN COMPANY (US) | 1994-04-14 | — | — | WO | claimed |