SCHEMBL8959189

SCHEMBL8959189

O=C(NCCOc1ccc(Oc2ccccc2)cc1Cl)C1CC1

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PKM P14618 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
NPC1 O15118 2/20 0.56
RAB9A P51151 2/20 0.56
EPHX2 P34913 1/20 0.56
KMT2A Q03164 3/20 0.49
MEN1 O00255 2/20 0.49
PTGDR2 Q9Y5Y4 1/20 0.49
ABL1 P00519 2/20 0.47
PPARA Q07869 7/20 0.46
PPARG P37231 4/20 0.46
PPARD Q03181 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8959068 0.91 ABL1 (0.53) PKMSMN1; SMN2NPC1RAB9AEPHX2
SCHEMBL8959041 0.91 PKM (0.56) PKMSMN1; SMN2NPC1RAB9AEPHX2
SCHEMBL8958993 0.89 ABL1 (0.51) PKMSMN1; SMN2NPC1RAB9AEPHX2
SCHEMBL8959167 0.89 KMT2A (0.50) PKMSMN1; SMN2NPC1RAB9AEPHX2
SCHEMBL8958875 0.87 MEN1 (0.50) PKMSMN1; SMN2NPC1RAB9AEPHX2
SCHEMBL8959169 0.87 NPC1 (0.52) PKMSMN1; SMN2NPC1RAB9AEPHX2
SCHEMBL8959049 0.87 PPARA (0.45) PKMSMN1; SMN2NPC1RAB9AEPHX2
SCHEMBL9165238 0.86 MEN1 (0.52) PKMSMN1; SMN2NPC1RAB9AKMT2A
SCHEMBL9730574 0.84 NPC1 (0.77) PKMSMN1; SMN2NPC1RAB9AEPHX2
SCHEMBL8959129 0.83 KMT2A (0.49) PKMSMN1; SMN2NPC1RAB9AEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0514833-B1 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL CO (JP) 1996-01-17 EP disclosed
US-5364966-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-11-15 US disclosed
US-5356930-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-10-18 US disclosed
EP-0514833-A2 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-11-25 EP disclosed