SCHEMBL8959201

SCHEMBL8959201

CC(=CC1(C)C2CC3CC(C2)CC1(C)C3)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.33
CYP2C9 P11712 1/20 0.33
CD81 P60033 1/20 0.31
APLNR P35414 1/20 0.31
EPHX1 P07099 1/20 0.30
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2406896 0.85 HSD11B1 (0.33) THRBCYP2C9CD81
SCHEMBL8595506 0.78 THRB (0.34) THRBCYP2C9CD81APLNREPHX1
SCHEMBL565405 0.75 CD81 (0.34) CD81APLNR
SCHEMBL1592699 0.75 CD81 (0.34) CD81APLNR
SCHEMBL757168 0.74 THRB (0.39) THRBCYP2C9CD81APLNREPHX1
SCHEMBL157720 0.74 THRB (0.39) THRBCYP2C9CD81APLNREPHX1
SCHEMBL701491 0.70 CD81 (0.31) CD81
SCHEMBL700264 0.70 HSD11B1 (0.32) CD81APLNR
SCHEMBL5935935 0.69 HSD11B1 (0.32) THRBCYP2C9EPHX1
SCHEMBL2406103 0.69 HSD11B1 (0.34) THRBCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5514753-A SYNTHETIC RUBBERS, FORMING LIVING POLYMERS BRIDGESTONE CORPORATION (JP) 1996-05-07 US disclosed