Hydrochloric Acid

Hydrochloric Acid

SCHEMBL8959268

CCCC[N+](CCCC)(CCCC)Cc1ccc(C)cc1.[Cl-]

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A1 O15245 3/20 0.42
PSMD14 O00487 1/20 0.42
HSP90AA1 P07900 1/20 0.42
MMP2 P08253 1/20 0.42
MC4R P32245 1/20 0.42
RAD52 P43351 1/20 0.42
HPGD P15428 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
TP53 P04637 1/20 0.41
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HTT P42858 3/20 0.40
KCNH2 Q12809 3/20 0.39
LMNA P02545 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
TSHR P16473 1/20 0.39
CYP2C19 P33261 1/20 0.39
HIF1A Q16665 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8664739 0.98 SLC22A1 (0.44) SLC22A1PSMD14HSP90AA1MMP2MC4R
SCHEMBL9409911 0.89 SLC22A1 (0.52) SLC22A1PSMD14HSP90AA1MMP2MC4R
SCHEMBL8671957 0.83 SLC22A1 (0.56) SLC22A1PSMD14HSP90AA1MMP2MC4R
SCHEMBL8671617 0.83 SLC22A1 (0.56) SLC22A1PSMD14HSP90AA1MMP2MC4R
SCHEMBL14948313 0.83 PSMD14 (0.43) SLC22A1PSMD14HSP90AA1MMP2MC4R
Tetrabuthylammonium SCHEMBL8027007 0.83 SLC22A1 (0.63) SLC22A1HPGDTP53SMN1; SMN2HTT
Hydrochloric Acid SCHEMBL8665765 0.82 PSMD14 (0.41) SLC22A1PSMD14HSP90AA1MMP2MC4R
Hydrochloric Acid SCHEMBL8959213 0.82 KCNH2 (0.56) SLC22A1PSMD14HSP90AA1MMP2MC4R
Hydrochloric Acid SCHEMBL194044 0.82 MEN1 (0.59) SLC22A1MEN1KMT2ATP53MAPK1
SCHEMBL12704909 0.80 CYP2A6 (0.43) SLC22A1HPGDTP53MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7076557-A None JP disclosed
US-5545502-A CONTAINING SPECIFIED QUATERNARY AMMONIUM SALT AS CHARGE CONTROL AGENT MITSUBISHI CHEMICAL CORPORATION (JP) 1996-08-13 US disclosed
EP-0602566-B1 Electrostatic image-developing toner MITSUBISHI CHEM CORP (JP) 1996-07-31 EP disclosed
JP-H0776557-A PRODUCTION OF QUATERNARY AMMONIUM COMPOUND MITSUBISHI CHEM CORP 1995-03-20 JP disclosed
EP-0602566-A1 Electrostatic image-developing toner Mitsubishi Chemical Corporation (JP) 1994-06-22 EP disclosed