Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 7/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329048 | 0.88 | CASP3 (0.41) | CASP3ITGB3ITGA2BPRMT5WDR77 | |
| SCHEMBL7325381 | 0.75 | ITGB3 (0.46) | CASP3ITGB3ITGA2BGABRA1GABRG2 | |
| Trifluoroacetic Acid SCHEMBL7323917 | 0.75 | ITGB3 (0.37) | ITGB3ITGA2BPRMT5WDR77GABRA1 | |
| SCHEMBL7357974 | 0.74 | ITGB3 (0.50) | ITGB3ITGA2B | |
| SCHEMBL7329841 | 0.73 | ITGB3 (0.44) | CASP3ITGB3ITGA2BPRMT5WDR77 | |
| SCHEMBL7319919 | 0.70 | ITGB3 (0.48) | CASP3ITGB3ITGA2BMDM2GABRA1 | |
| SCHEMBL2833423 | 0.68 | CASP3 (0.51) | CASP3MAPTALDH1A1 | |
| SCHEMBL7322279 | 0.67 | MEN1 (0.40) | CASP3ITGB3ITGA2BMDM2TP53 | |
| SCHEMBL1500258 | 0.67 | SDCBP (0.52) | PRMT5WDR77DPP7DNMT1KDM4E | |
| SCHEMBL8959460 | 0.67 | KDM4E (0.47) | ITGB3ITGA2BMDM2TP53DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610334-B1 | NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPII B III A RECEPTOR | GENENTECH INC (US) | 1996-01-24 | — | — | EP | disclosed |