Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960014 | 0.78 | METAP1 (0.39) | LMNAGAAMAPT | |
| SCHEMBL8959924 | 0.77 | AAK1 (0.36) | HPGDHSD17B10MAPT | |
| SCHEMBL13797360 | 0.75 | MAPT (0.56) | LMNAGFERGAAMAPT | |
| SCHEMBL2706594 | 0.75 | LMNA (0.41) | LMNA | |
| SCHEMBL8960053 | 0.74 | KCNJ1 (0.36) | LMNAGAAMAPTTRPA1 | |
| SCHEMBL24102223 | 0.73 | LMNA (0.47) | LMNANPSR1HPGDGFERHSD17B10 | |
| SCHEMBL13070980 | 0.71 | MAPT (0.42) | HPGDHSD17B10GAAMAPT | |
| SCHEMBL2756745 | 0.70 | LMNA (0.41) | LMNA | |
| SCHEMBL8959916 | 0.69 | MAOA (0.40) | GAAMAPT | |
| SCHEMBL8960097 | 0.69 | GPR3 (0.39) | LMNAHSD17B10PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510456-A | Bridged cyclic arleneethylene polymers | SHOWA DENKO K. K. (JP) | 1996-04-23 | — | — | US | disclosed |