Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 7/20 | 0.61 |
| ▸ | HTR7 | P34969 | 1/20 | 0.59 |
| ▸ | THRA | P10827 | 6/20 | 0.51 |
| ▸ | THRB | P10828 | 6/20 | 0.51 |
| ▸ | STS | P08842 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8114139 | 0.95 | HSD17B3 (0.62) | HSD17B3HTR7THRATHRBSTS | |
| SCHEMBL9335675 | 0.93 | HSD17B3 (0.63) | HSD17B3HTR7THRATHRBSTS | |
| SCHEMBL9335705 | 0.93 | HSD17B3 (0.63) | HSD17B3HTR7THRATHRBSTS | |
| SCHEMBL8083048 | 0.89 | HSD17B3 (0.58) | HSD17B3HTR7THRATHRBSTS | |
| SCHEMBL30089557 | 0.87 | PTGS1 (0.53) | L3MBTL1 | |
| SCHEMBL28704369 | 0.85 | HTR7 (0.62) | HSD17B3HTR7THRATHRBSTS | |
| SCHEMBL14522305 | 0.83 | HSD17B3 (0.83) | HSD17B3HTR7THRATHRBSTS | |
| SCHEMBL14297902 | 0.82 | BLM (0.55) | L3MBTL1 | |
| SCHEMBL9441163 | 0.82 | TRPA1 (0.53) | — | |
| SCHEMBL8123386 | 0.82 | HSD17B3 (0.69) | HSD17B3HTR7THRATHRBSTS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530019-A | FOR TREATMENT OF PROSTATE GLAND DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-06-25 | — | — | US | disclosed |
| EP-0648208-A1 | INDOLE DERIVATIVES AS TESTOSTERONE 5 ALPHA-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994022821-A1 | INDOLE DERIVATIVES AS TESTOSTERONE 5 ALPHA-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-13 | — | — | WO | disclosed |
| EP-0603278-A1 | INDOLE DERIVATIVES AS 5-ALPHA-REDUCTASE INHIBITOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-29 | — | — | EP | disclosed |
| US-5312829-A | Testosterone 5alpha-reductase inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| US-5212320-A | Enzyme inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-05-18 | — | — | US | disclosed |
| WO-1993005019-A1 | INDOLE DERIVATIVES AS 5-ALPHA-REDUCTASE INHIBITOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-18 | — | — | WO | disclosed |