Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 2/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | PRF1 | P14222 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8959924 | 0.83 | AAK1 (0.36) | MAPTSMN1; SMN2HPGDALDH1A1KDM4E | |
| SCHEMBL8959917 | 0.83 | MAOA (0.42) | MAPTHPGDALDH1A1CYP1A2MEN1 | |
| SCHEMBL8960058 | 0.81 | MEN1 (0.42) | MAPTALDH1A1NPC1RAB9AGAA | |
| SCHEMBL8960014 | 0.78 | METAP1 (0.39) | MAPTSMN1; SMN2ALDH1A1KDM4ERAB9A | |
| SCHEMBL6661823 | 0.75 | PRF1 (0.65) | MAPTSMN1; SMN2HPGDALDH1A1KDM4E | |
| SCHEMBL8960053 | 0.74 | KCNJ1 (0.36) | MAPTSMN1; SMN2ALDH1A1KDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL584636 | 0.73 | MAPT (0.47) | MAPTSMN1; SMN2HPGDALDH1A1KDM4E | |
| SCHEMBL26767732 | 0.73 | METAP1 (0.49) | MAPTSMN1; SMN2HPGDALDH1A1KDM4E | |
| SCHEMBL29853706 | 0.71 | MAPT (0.58) | MAPTSMN1; SMN2HPGDALDH1A1KDM4E | |
| SCHEMBL26767260 | 0.71 | MAPT (0.58) | MAPTSMN1; SMN2HPGDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510456-A | Bridged cyclic arleneethylene polymers | SHOWA DENKO K. K. (JP) | 1996-04-23 | — | — | US | disclosed |